Diagnostic and Biological Sciences

Projects and Grants

Projects per year 1984 2009 2010 2011 2013 2016 2017 2020 2028

• 38 Active
• 237 Finished

Projects per year

Search results

• Finished

  Imaging of HTLV-1 by cryo-CLEM

  Mansky, L. M.

  National Institute of Dental and Craniofacial Research

  5/1/23 → 4/30/24

  Project: Research project

  • Human T-lymphotropic virus 1 100%
  • Virion 23%
  • Synapses 22%
  • Workflow 16%
  • Virus Assembly 15%

• Phase 2/3: ?Double-Blind, Randomized, Placebo Controlled, Safety and Efficacy Trial of BHV-3000 (rimegepant) Orally Disintegrating Tablet (ODT) for the Acute Treatment of Temporomandibular Disorders (TMD)

  Nixdorf, D. R.

  BIOHAVEN PHARMACEUTICALS LLC

  1/1/22 → 8/31/23

  Project: Research project

  • (5S,6S,9R)-5-amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta(b)pyridin-9-yl 4-(2-oxo-2,3-dihydro-1H-imidazo(4,5-b)pyridin-1-yl)piperidine-1-carboxylate 100%
  • Temporomandibular Joint Disorders 58%
  • Tablets 43%
  • Placebos 32%
  • Safety 27%

• Calprotectin-mediated CD69 signaling in periodontitis

  Costalonga, M.

  National Institute of Dental and Craniofacial Research

  7/1/21 → 3/31/24

  Project: Research project

  • Leukocyte L1 Antigen Complex 100%
  • Periodontitis 95%
  • Th17 Cells 73%
  • Regulatory T-Lymphocytes 61%
  • Porphyromonas gingivalis 57%

• Calprotectin and CD69 affect regulatory T cell responses in periodontal disease

  Costalonga, M., Bittner-Eddy, P., Herzberg, M. C. & Johnstone, K. F.

  NIH NIDCR NATL INST OF DENTAL

  4/1/21 → 3/31/24

  Project: Research project

  • Leukocyte L1 Antigen Complex 100%
  • Periodontal Diseases 78%
  • Regulatory T-Lymphocytes 72%

• Calprotectin and CD69 affect regulatory T cell responses in periodontal disease

  Costalonga, M.

  National Institute of Dental and Craniofacial Research

  4/1/21 → 3/31/23

  Project: Research project

  • Leukocyte L1 Antigen Complex 100%
  • Regulatory T-Lymphocytes 57%
  • Periodontitis 55%
  • Periodontal Diseases 54%
  • Gingiva 23%

• Epstein-Barr Virus nuclear antigen leader protein in transcription regulation

  Wang, C.

  National Institute of Dental and Craniofacial Research

  2/1/21 → 1/31/23

  Project: Research project

  • Epstein-Barr Virus Nuclear Antigens 100%
  • Hairy Tongue 39%
  • Hairy Leukoplakia 31%
  • Infectious Mononucleosis 26%
  • Proteins 25%

• Brain Connectivity Patterns in Chronic Temporomandibular Joint Disorders

  Moana Filho, E. J.

  National Institute of Dental and Craniofacial Research

  9/1/20 → 8/31/23

  Project: Research project

  • Temporomandibular Joint Disorders 100%
  • Muscular Diseases 68%
  • Brain 40%
  • Pain 39%
  • Myalgia 28%

• Cryo-ET Guided Single Particle Reconstruction of HIV

  Zhang, W. & Mansky, L. M.

  NIH Nat'l Inst of Allergy & Infect Dis

  8/21/20 → 7/31/23

  Project: Research project

  • HIV 100%

• Cryo-ET Guided Single Particle Reconstruction of HIV

  Zhang, W. & Mansky, L. M.

  National Institute of Allergy and Infectious Diseases

  8/21/20 → 7/31/21

  Project: Research project

  • HIV-1 100%
  • Retroviridae 99%
  • Electron Microscope Tomography 68%
  • Deltaretrovirus 63%
  • HIV-2 59%

• A novel, two-armed autotherapy for mucosal infectious diseases

  Herzberg, M. C.

  NIH NIDCR NATL INST OF DENTAL

  8/5/20 → 1/31/24

  Project: Research project

  • Communicable Diseases 100%

• A novel, two-armed autotherapy for mucosal infectious diseases

  Herzberg, M. C.

  National Institute of Dental and Craniofacial Research

  8/5/20 → 7/31/21

  Project: Research project

  • Periodontitis 100%
  • Communicable Diseases 88%
  • Messenger RNA 62%
  • Alveolar Bone Loss 48%
  • Microbiota 36%

• MHC-II deficient Langerhans cells with compensatory Tc17 plasticity in oral candidiasis

  Costalonga, M. & Bittner-Eddy, P.

  NIH NIDCR NATL INST OF DENTAL

  7/1/20 → 6/30/23

  Project: Research project

  • Oral Candidiasis 100%
  • Langerhans Cells 89%

• MHC-II deficient Langerhans cells with compensatory Tc17 plasticity in oral candidiasis

  Costalonga, M.

  National Institute of Dental and Craniofacial Research

  7/1/20 → 6/30/22

  Project: Research project

  • Langerhans Cells 100%
  • Oral Candidiasis 84%
  • Candida albicans 48%
  • Mouth Mucosa 35%
  • Interleukin-17 34%

• Immunoregulatory role of PMN leukocytes in periodontitis

  Bittner-Eddy, P. & Costalonga, M.

  NIH NIDCR NATL INST OF DENTAL

  5/1/20 → 4/30/23

  Project: Research project

  • Periodontitis 100%
  • Leukocytes 72%

• Immunoregulatory role of PMN leukocytes in periodontitis

  Bittner-Eddy, P.

  National Institute of Dental and Craniofacial Research

  5/1/20 → 4/30/22

  Project: Research project

  • Periodontitis 100%
  • Porphyromonas gingivalis 93%
  • Neutrophils 89%
  • Myeloid-Derived Suppressor Cells 88%
  • Leukocytes 62%

• Pre-clinical development of antimicrobial peptides

  Gorr, S.

  ACADEMIC CONSORTIUM 21

  4/1/20 → 9/21/21

  Project: Research project

  • antimicrobial peptides 100%

• Molecular Determinants of Retroviral Gag Capsid Morphology

  Talledge, N. L.

  NIH Nat'l Inst of Allergy & Infect Dis

  3/17/20 → 2/28/22

  Project: Research project

  • Capsid 100%

• Theiler's virus RNA in exosomes secreted by infected microglia

  Olson, J.

  NIH Nat'l Inst of Allergy & Infect Dis

  3/12/20 → 2/29/24

  Project: Research project

  • Exosome Multienzyme Ribonuclease Complex 100%
  • Theilovirus 91%
  • Microglia 61%

• Theiler's virus RNA in exosomes secreted by infected microglia

  Olson, J.

  National Institute of Allergy and Infectious Diseases

  3/12/20 → 2/28/21

  Project: Research project

  • Theilovirus 100%
  • Exosome Multienzyme Ribonuclease Complex 93%
  • Microglia 68%
  • Viral RNA 45%
  • Demyelinating Diseases 37%

• Assessing the Role of Ne-Lysine Acetylation on Streptococcus gordonii Biofilms

  Lima, B.

  INTERNATIONAL ASSOC FOR DENTAL RESEARCH

  3/5/20 → 9/4/21

  Project: Research project

  • Streptococcus gordonii 100%
  • Acetylation 67%
  • Biofilms 62%
  • Lysine 62%

• Comparative human retroviral assembly in the context of cell polarization

  Hanson, H. M. & Mansky, L. M.

  NIH Nat'l Inst of Allergy & Infect Dis

  9/30/19 → 9/29/23

  Project: Research project

  • polarization 100%

• HIV Gag lattice morphology and particle biogenesis

  Mansky, L. M. & Mueller, J. D.

  National Institute of Allergy and Infectious Diseases

  9/1/19 → 8/31/21

  Project: Research project

  • Retroviridae 100%
  • HIV-1 64%
  • Virus Replication 55%
  • HIV 46%
  • Electron Microscope Tomography 27%

• Contribution of endocannabinoid signaling to the antihyperalgesic effect of spinal cord stimulation in a model of neuropathic pain

  Simone, D. A.

  INT'L ASSOCIATION FOR THE STUDY OF PAIN

  7/1/19 → 12/31/21

  Project: Research project

  • Spinal Cord Stimulation 100%
  • Endocannabinoids 91%
  • Neuralgia 77%

• The Bumps, a device for rapid, non invasive quantification of touch sensation

  Kennedy, W. R. & Loavenbruck, A. J.

  Neuro Devices, Inc., NIH NAT'L CTR FOR ADVANCING TRAN SCIENCE

  4/11/19 → 3/31/23

  Project: Research project

• Diagnostic Accuracy of MRI to Detect Vertical Root Fractures in Extracted Endodontically Treated Teeth

  Groenke, B. R. & Nixdorf, D. R.

  AMERICAN ACADEMY OF ORALFACIAL PAIN

  4/1/19 → 6/30/21

  Project: Research project

  • teeth 100%

• Probabilistic multifactorial lifetime assessment for resin-based composite restorations

  Fok, A., Aparicio, C. & Rudney, J. D.

  NIH NIDCR NATL INST OF DENTAL

  2/1/19 → 1/31/23

  Project: Research project

  • Restoration 100%
  • Resins 91%
  • Composite materials 59%

• Cellular determinants of HIV mutagenesis

  Meissner, M. E. & Mansky, L. M.

  NIH NIGMS NATL INST OF GENERAL

  2/1/19 → 6/30/21

  Project: Research project

  • Mutagenesis 100%
  • HIV 69%

• Nonviral Topical Transfection with Calprotectin in Periodontitis

  Boyle, W.

  NIH NIDCR NATL INST OF DENTAL

  12/3/18 → 5/2/21

  Project: Research project

  • Leukocyte L1 Antigen Complex 100%
  • Periodontitis 79%
  • Transfection 62%

• Investigating the role of lipoteichoic acid in surface protein presentation

  Lima, B.

  NIH NIDCR NATL INST OF DENTAL

  9/18/18 → 8/31/23

  Project: Research project

  • acids 100%
  • proteins 89%

• Brain Connectivity Patterns in Chronic Temporomandibular Joint Disorders

  Moana Filho, E. J.

  NIH NIDCR NATL INST OF DENTAL

  9/18/18 → 8/31/20

  Project: Research project

  • Temporomandibular Joint Disorders 100%
  • Brain 39%

• Investigating the role of lipoteichoic acid in surface protein presentation

  Lima, B.

  National Institute of Dental and Craniofacial Research

  9/18/18 → 8/31/23

  Project: Research project

  • acids 100%
  • proteins 89%
  • lipoproteins 40%
  • physiology 36%
  • viability 30%

• Brain Connectivity Patterns in Chronic Temporomandibular Joint Disorders

  Moana Filho, E. J.

  National Institute of Dental and Craniofacial Research

  9/18/18 → 8/31/20

  Project: Research project

  • Temporomandibular Joint Disorders 100%
  • Muscular Diseases 68%
  • Brain 39%
  • Pain 36%
  • Myalgia 30%

• Mechanisms of Viral DNA Packaging - UCBerkeley - Resubmission

  Jardine, P. J. & Grimes, S. N.

  UNIVERSITY OF CALIFORNIA, BERKELEY, NATIONAL INSTITUTES OF HEALTH (NIH)

  8/17/18 → 7/31/19

  Project: Research project

  • DNA Packaging 100%
  • Virus Assembly 87%
  • Viral DNA 75%

• Mechanisms to predict and potentiate acupuncture analgesia in sickle cell disease

  Wang, Y.

  NATIONAL INSTITUTES OF HEALTH (NIH)

  7/17/18 → 6/30/21

  Project: Research project

  • Acupuncture Analgesia 100%
  • Sickle Cell Anemia 69%

• Mechanisms to predict and potentiate acupuncture analgesia in sickle cell disease

  Wang, Y.

  National Center for Complementary and Integrative Health

  7/17/18 → 6/30/21

  Project: Research project

  • Acupuncture Analgesia 100%
  • Sickle Cell Anemia 82%
  • Electroacupuncture 78%
  • Mentors 74%
  • Pain 48%

• Hyperalgesia following activation of Nav1.8 ion channels

  Simone, D. A.

  MERCK

  5/1/18 → 12/1/20

  Project: Research project

  • Hyperalgesia 100%
  • Ion Channels 91%

• Ex vivo and In vivo Dental MRI Imaging of Blood Flow in

  Gaalaas, L. R.

  THEAMERICAN ACADEMY OF ORAL AND

  3/15/18 → 6/30/21

  Project: Research project

  • Flow 100%

• Dermal Interface

  Gorr, S., Aparicio, C., Kidwai, F. K. & Kidwai, F. K.

  HENNEPIN HEALTHCARE RESEARCH INSTITUTE, USDOD NAVY

  10/1/17 → 9/14/23

  Project: Research project

• HIV Gag lattice morphology and particle biogenesis

  Mansky, L. M. & Zhang, W.

  NIH NIGMS NATL INST OF GENERAL

  9/30/17 → 8/31/23

  Project: Research project

  • HIV 100%

• Ocular Hyperalgesia in Dry Eye

  Bereiter, D. A. & Olson, J.

  NATIONAL INSTITUTES OF HEALTH (NIH)

  9/30/17 → 4/30/22

  Project: Research project

  • eyes 100%

• Ocular Hyperalgesia in Dry Eye

  Bereiter, D. A.

  National Eye Institute

  9/30/17 → 4/30/21

  Project: Research project

  • Hyperalgesia 93%
  • Eye 62%
  • Microglia 46%
  • Neurons 39%
  • Tears 35%

• HIV Gag lattice morphology and particle biogenesis - Administrative Supplement

  Mansky, L. M. & Mueller, J. D.

  National Institute of General Medical Sciences

  9/30/17 → 8/31/19

  Project: Research project

  • Retroviridae 100%
  • HIV-1 64%
  • Virus Replication 55%
  • HIV 51%
  • Electron Microscope Tomography 27%

• The Restful Jaw Device: A New Way to Support and Protect the Jaw During Third Molar Extractions

  Schiffman, E. L.

  National Institute of Dental and Craniofacial Research

  9/13/17 → 8/31/18

  Project: Research project

  • Jaw 100%
  • Third Molar 67%
  • Equipment and Supplies 47%
  • Deep Sedation 39%
  • Conscious Sedation 36%

• Probabilistic multifactorial lifetime for resin-based co

  Fok, A., Aparicio, C. & Rudney, J. D.

  NIH NIDCR NATL INST OF DENTAL

  9/7/17 → 1/31/19

  Project: Research project

  • Resins 100%
  • Restoration 54%
  • Composite materials 32%

• The DNA Packaging Motor of Bacteriophage phi29

  Jardine, P. J.

  NIH NIGMS NATL INST OF GENERAL

  9/1/17 → 9/16/21

  Project: Research project

  • DNA Packaging 100%
  • Bacteriophages 66%

• Collaborative Research: Physical parameters controlling

  Jardine, P. J. & Grimes, S. N.

  THE NATIONAL SCIENCE FOUNDATION

  8/1/17 → 7/31/22

  Project: Research project

  • DNA Packaging 100%
  • Virus Assembly 87%
  • Viral DNA 75%
  • Infections 32%

• Role of purinergic signaling and glia in TMJ nociception

  Bereiter, D. A. & Olson, J.

  NIH NIDCR NATL INST OF DENTAL

  8/1/17 → 7/31/19

  Project: Research project

  • Nociception 100%
  • Temporomandibular Joint 97%
  • Neuroglia 74%

• HTLV-1 Particle Analysis and Gag Interactions

  Mansky, L. M., Mueller, J. & Zhang, W.

  NIH NIGMS NATL INST OF GENERAL

  8/1/17 → 4/30/23

  Project: Research project

  • Human T-lymphotropic virus 1 100%

• Collaborative Research: Physical parameters controlling viral DNA packaging and ejection

  Jardine, P. J.

  National Science Foundation

  8/1/17 → 7/31/22

  Project: Research project

  • DNA Packaging 100%
  • Virus Assembly 93%
  • Viral DNA 75%
  • Product Packaging 67%
  • DNA 65%

• Role of purinergic signaling and glia in TMJ nociception

  Bereiter, D. A.

  National Institute of Dental and Craniofacial Research

  8/1/17 → 7/31/19

  Project: Research project

  • Temporomandibular Joint 100%
  • Nociception 63%
  • Neuroglia 59%
  • Temporomandibular Joint Disorders 39%
  • Neurons 39%