Genetics, Cell Biology and Development (CBS)

Projects and Grants

Projects per year 1985 2010 2011 2015 2017 2018 2019 2021 2022 2023 2029

• 71 Active
• 256 Finished

Projects per year

Search results

• Finished

  Pushing It Forward: Cell Movement in Development

  Nakato, H.

  THE COMPANY OF BIOLOGISTS LTD.

  7/6/23 → 1/2/24

  Project: Research project

  • Cell Movement 100%

• Mob4 activity and dysfunction in Alzheimer's Disease

  Neisch, A. L.

  National Institute on Aging

  7/1/23 → 3/31/24

  Project: Research project

  • Phosphotransferases 100%
  • Alzheimer Disease 71%
  • Axonal Transport 23%
  • Neurons 22%
  • Microtubule-Associated Proteins 21%

• Conference: An International Conference on Engineering Synthetic Cells and Organelles

  Adamala, K. & Sorenson Johnson, C. E.

  THE NATIONAL SCIENCE FOUNDATION

  4/1/23 → 3/31/24

  Project: Research project

  • International Conference 100%

• Conference: An International Conference on Engineering Synthetic Cells and Organelles

  Adamala, K.

  National Science Foundation

  4/1/23 → 3/31/24

  Project: Research project

  • Containment of Biohazards 100%
  • Synthetic biology 84%
  • Ethical aspects 74%
  • Metabolism 72%
  • Chassis 64%

• Caenorhabditis Genetics Center

  Rougvie, A. E.

  NIH Office of the Director

  3/1/23 → 2/29/24

  Project: Research project

  • Caenorhabditis 100%
  • Caenorhabditis elegans 30%
  • labor 16%
  • researchers 15%
  • Nematoda 15%

• Enhancing and expanding the CGC Strain Collection

  Rougvie, A. E.

  NIH Office of the Director

  3/1/23 → 2/29/24

  Project: Research project

  • Caenorhabditis 100%
  • Caenorhabditis elegans 52%
  • Proteins 30%
  • Caenorhabditis elegans Proteins 18%
  • Green Fluorescent Proteins 12%

• Impact of dilated cardiomyopathy mutations on cardiac myosin structure and function

  Yengo, C. M., Warshaw, D. M. & Sivaramakrishnan, S.

  National Heart, Lung, and Blood Institute

  12/15/22 → 11/30/23

  Project: Research project

  • Myosins 100%
  • Cardiac Myosins 93%
  • Dilated Cardiomyopathy 56%
  • Mutation 47%
  • Head 38%

• Mapping the experimental boundaries for controllable synthetic cell cycle

  Adamala, K.

  ALFRED P. SLOAN FOUNDATION

  9/1/22 → 8/31/23

  Project: Research project

  • Cells 100%

• Genetic Counseling Fellowship in Research Training (GC-FIRST)

  Zierhut, H.

  National Human Genome Research Institute

  6/15/22 → 3/31/24

  Project: Research project

  • Genetic Counseling 100%
  • Counselors 88%
  • Genetic Research 35%
  • Industry 26%
  • Population Health 20%

• Applications of Advanced Phenotyping and Genome Editing to Accelerate Genetic Gains in Tef Breeding in Ethiopia

  Voytas, D. F.

  DONALD DANFORTH PLANT SCIENCE CENTER, CORTEVA, INC

  3/1/22 → 12/31/23

  Project: Research project

  • Eragrostis tef 100%
  • gene editing 87%
  • genetic improvement 66%
  • phenotype 46%
  • breeding 42%

• Antibody-AAV composites for hematopoietic stem cell targeting in vivo

  Hoffmann, M. D.

  AMERICAN SOCIETY OF GENE & CELL THERAPY

  12/1/21 → 11/30/22

  Project: Research project

  • Hematopoietic Stem Cells 100%
  • Antibodies 55%

• UV-Induced DNA Damage as a Means of Measuring Exoplanet Habitability

  Engelhart, A. E.

  THE HEISING-SIMONS FOUNDATION

  10/1/21 → 9/30/23

  Project: Research project

  • DNA damage 100%

• Sculpting living form: Mechanotransduction and development

  Nakato, H.

  THE COMPANY OF BIOLOGISTS LTD.

  7/16/21 → 11/30/22

  Project: Research project

• I-Corps: Viral vector platform technology for cell type-specific gene delivery

  Schmidt, D., McIvor, R. S. & Zdechlik, A. C.

  THE NATIONAL SCIENCE FOUNDATION

  6/1/21 → 11/30/22

  Project: Research project

  • Technology 100%
  • Genes 61%

• I-Corps: Viral vector platform technology for cell type-specific gene delivery

  Schmidt, D.

  National Science Foundation

  6/1/21 → 11/30/22

  Project: Research project

  • Dependovirus 100%
  • Technology 68%
  • Genetic Therapy 59%
  • Antibodies 53%
  • Genes 33%

• Genetics and genomics of human breast milk composition

  Johnson, K. E.

  NIH NAT'L INST OF CHILD HEALTH/HUMAN DEV

  5/1/21 → 8/31/23

  Project: Research project

  • breast milk 100%
  • milk composition 96%
  • genomics 59%

• Genetics and genomics of human breast milk composition

  Johnson, K. E.

  National Institute of Child Health and Human Development, Eunice Kennedy Shriver National Institute of Child Health and Human Development

  5/1/21 → 8/31/23

  Project: Research project

  • milk composition 100%
  • breast milk 80%
  • milk 54%
  • genomics 52%
  • microbiome 45%

• Cell-free investigations of Interactions between drug-like molecules and G-Quadruplexes in mRNA

  Engelhart, A. E.

  ARRAKIS THERAPEUTICS, INC

  9/9/20 → 9/8/22

  Project: Research project

  • G-Quadruplexes 100%
  • Drug Interactions 66%
  • Messenger RNA 39%

• Live-cell investigations of Interactions between drug-like molecules and G-Quadruplexes in mRNA

  Engelhart, A. E.

  ARRAKIS THERAPEUTICS, INC

  9/9/20 → 9/8/22

  Project: Research project

  • G-Quadruplexes 100%
  • Cell Communication 64%
  • Messenger RNA 39%
  • Pharmaceutical Preparations 28%

• Optima AUC analytical ultracentrifuge

  Courtemanche, N.

  NIH Office of the Director

  8/26/20 → 8/25/21

  Project: Research project

  • Area Under Curve 100%

• Optima AUC analytical ultracentrifuge

  Courtemanche, N.

  NIH Office of the Director

  8/26/20 → 8/25/21

  Project: Research project

  • Area Under Curve 100%
  • Research Personnel 38%
  • Muscular Dystrophies 32%
  • Hydrodynamics 31%
  • Drug Delivery Systems 27%

• NSF Postdoctoral Fellowship in Biology FY 2020: Developmental Regulator-Mediated Gene Editing: A Method to Improve Accessibility and Production of Transgenic Plants

  Cody, J.

  National Science Foundation

  8/1/20 → 7/31/23

  Project: Research project

  • gene editing 100%
  • genetic engineering 95%
  • meristems 82%
  • transgenic plants 82%
  • Biological Sciences 58%

• Drug Discovery for Spinocerebellar Ataxia, using Novel Fluorescence Technology Targeting ?-III-Spectrin

  Hays, T. S.

  National Institute of Neurological Disorders and Stroke

  5/1/20 → 4/30/22

  Project: Research project

  • Spectrin 100%
  • Spinocerebellar Ataxias 87%
  • Actins 71%
  • Fluorescence Resonance Energy Transfer 69%
  • Drug Discovery 62%

• Drosophila cryopreservation and rewarming for long-term storage

  Bischof, J. C. & Hays, T. S.

  NIH Office of the Director

  3/15/20 → 2/29/24

  Project: Research project

  • cryopreservation 100%
  • Drosophila 85%

• Comparative human retroviral assembly in the context of cell polarization

  Hanson, H. M.

  National Institute of Allergy and Infectious Diseases

  9/30/19 → 9/29/23

  Project: Research project

  • T-Cell Leukemia 100%
  • Retroviridae 98%
  • Deltaretrovirus 95%
  • HIV-1 92%
  • Viruses 79%

• Control of Meiosis and Germline Proliferation

  Greenstein, D. I., Spike, C. A. & Tsukamoto, T.

  NIH NIGMS NATL INST OF GENERAL

  9/15/19 → 7/31/22

  Project: Research project

  • Meiosis 100%

• A life course perspective on the effects of cumulative early adversity on health

  Blekhman, R. & Khoruts, A.

  UNIVERSITY OF NOTRE DAME, NATIONAL INSTITUTES OF HEALTH (NIH)

  8/1/19 → 5/31/22

  Project: Research project

  • health 100%

• Drug discovery for spinocerebellar ataxia, using novel fluorescence technology targeting B-III-spectrin

  Hays, T. S., Avery, A. & Thomas, D. D.

  NIH NAT INST OF NEURO DISORDERS & STROKE

  5/1/19 → 4/30/23

  Project: Research project

  • Spinocerebellar Ataxias 100%
  • Spectrin 97%
  • Drug Discovery 76%
  • Fluorescence 60%
  • Technology 48%

• Mechanisms that Regulate Intracellular Transport

  Hays, T. S., Parker, L. L. & Thomas, D. D.

  NIH NIGMS NATL INST OF GENERAL

  5/1/19 → 1/31/24

  Project: Research project

• Drug discovery for spinocerebellar ataxia, using novel fluorescence technology targeting ?-III-spectrin

  Hays, T. S.

  National Institute of Neurological Disorders and Stroke

  5/1/19 → 4/30/20

  Project: Research project

  • Spectrin 100%
  • Spinocerebellar Ataxias 79%
  • Actins 75%
  • Fluorescence Resonance Energy Transfer 73%
  • Drug Discovery 53%

• Heparan sulfate proteoglycans in signaling and development

  Nakato, H.

  National Institute of General Medical Sciences

  5/1/19 → 4/30/24

  Project: Research project

  • Heparan Sulfate Proteoglycans 100%
  • Drosophila 52%
  • Chondroitin Sulfate Proteoglycans 23%
  • Proteoglycans 18%
  • Hedgehogs 11%

• Tissue culture free gene editing in canola and grape

  Voytas, D. F. & Clark, M.

  TECHACCEL, LLC

  4/19/19 → 12/31/19

  Project: Research project

  • gene editing 100%
  • canola 88%
  • tissue culture 73%
  • grapes 73%

• Elucidating Molecular Mechanisms of Hypertrophic Cardiomyopathy using Nano-Engineered Synthetic Myosin Thick Filaments

  Touma, A. M.

  NIH NAT'L HEART, LUNG, AND BLOOD INSTITU

  2/18/19 → 2/17/23

  Project: Research project

  • myosins 100%
  • filaments 66%

• Genetic Influences on Protein Degradation in Large Yeast Populations

  Collins, M. A.

  NIH NIGMS NATL INST OF GENERAL

  2/4/19 → 2/3/20

  Project: Research project

  • Proteolysis 100%
  • Yeasts 85%
  • Population 41%

• Conserved torsinA-interacting proteins and the control of nuclear envelope function in the nematode Caenorhabditis elegans

  Huelgas Morales, G.

  DYSTONIA MEDICAL RESEARCH FDN

  2/4/19 → 2/3/21

  Project: Research project

  • Nuclear Envelope 100%
  • Caenorhabditis elegans 96%
  • Proteins 32%

• Genetic Influences on Protein Degradation in Large Yeast Populations

  Collins, M. A.

  National Institute of General Medical Sciences

  2/4/19 → 2/3/20

  Project: Research project

  • Proteolysis 100%
  • Yeasts 55%
  • Quantitative Trait Loci 49%
  • Ubiquitin 47%
  • Proteasome Endopeptidase Complex 32%

• Fluorescent RNA in space: High school student-designed experiments to probe the impact of spaceflight on human health

  Engelhart, A. E.

  THE MINDLIN FOUNDATION

  1/1/19 → 12/31/19

  Project: Research project

  • Space Flight 100%
  • Students 54%
  • RNA 53%
  • Health 37%

• Exploring the Informational Transitions Bridging Inorganic Chemistry and Minimal Life

  Adamala, K.

  ARIZONA STATE UNIVERSITY, JOHN TEMPLETON FOUNDATION

  11/1/18 → 10/31/21

  Project: Research project

  • chemistry 100%

• Bringing Telegenetics to the Upper Midwest - A one-day telehealth workshop and year long follow-up to increase knowledge, use, and overcome barriers to implementing telegenetics services

  Zierhut, H.

  MICHIGAN PUBLIC HEALTH INSTITUTE, US Dept. of Health & Human Services HRSA

  10/1/18 → 5/31/19

  Project: Research project

  • services 100%

• SemiSynBio-Very large-scale genetic circuit design automation

  Adamala, K.

  THE NATIONAL SCIENCE FOUNDATION

  10/1/18 → 9/30/22

  Project: Research project

  • Automation 100%

• SemiSynBio: Collaborative Research: Very Large-Scale Genetic Circuit Design Automation

  Adamala, K.

  National Science Foundation

  10/1/18 → 9/30/22

  Project: Research project

  • Networks (circuits) 100%
  • Automation 88%
  • Molecules 54%
  • Synthetic biology 41%
  • Electronic design automation 41%

• Compartmentalized evolution of the translation machinery

  Alejo Amaya, J. L.

  HOWARD HUGHES MEDICAL INSTITUTE

  9/26/18 → 9/25/22

  Project: Research project

• TorsinA-dependent signal transduction and DYT1 dystonia

  Luxton, G. W. G. & Mueller, J.

  NIH NIGMS NATL INST OF GENERAL

  9/17/18 → 6/7/20

  Project: Research project

• Genetic mapping of cellular trait variation in single human individuals

  Albert, F. W. & Tolar, J.

  NIH NHGRI NATL HUMAN GENOME RE

  9/17/18 → 8/31/21

  Project: Research project

  • chromosome mapping 100%

• Genetic mapping of cellular trait variation in single human individuals

  Albert, F. W. & Tolar, J.

  National Human Genome Research Institute

  9/17/18 → 8/31/21

  Project: Research project

  • chromosome mapping 100%
  • induced pluripotent stem cells 35%
  • proteins 31%
  • genomics 29%
  • human cell lines 28%

• Genomic Approaches for Regulatory Genetic Variation

  Albert, F. W.

  ALFRED P. SLOAN FOUNDATION

  9/15/18 → 9/14/20

  Project: Research project

  • genomics 100%
  • genetic variation 98%

• RoL:FELS:RAISE: Building and Modeling Synthetic Bacterial Cells

  Adamala, K.

  J. CRAIG VENTER INSTITUTE, THE NATIONAL SCIENCE FOUNDATION

  9/1/18 → 8/31/23

  Project: Research project

  • Artificial Cells 100%

• HHMI Gilliam Graduate Fellowship - Mapping Engineerable Allostery in Ion Channels

  Coyote-Maestas, W.

  HOWARD HUGHES MEDICAL INSTITUTE

  9/1/18 → 8/31/21

  Project: Research project

  • Ion Channels 100%

• RoL: RAISE: DESYN-C3: Engineering multi-compartmentalised synthetic minimal cells

  Adamala, K.

  PENNSYLVANIA STATE UNIVERSITY, THE NATIONAL SCIENCE FOUNDATION

  9/1/18 → 12/31/23

  Project: Research project

  • Artificial Cells 100%

• Engineering "Species-like" Barriers to Sexual Reproduction to Prevent Gene Flow in Plants

  Smanski, M. J. & Voytas, D. F.

  USDA Nat'l Inst. of Food & Agriculture

  9/1/18 → 8/31/22

  Project: Research project

  • sexual reproduction 100%
  • engineering 84%
  • gene flow 84%