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Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Dive into the research topics where Michael F Freeman is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Projects and Grants
- 2 Active
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Discovery and characterization of biocatalysts for ribosomally encoded alpha-N-methylated peptide natural products
NIH NIGMS NATL INST OF GENERAL
8/1/19 → 5/31/24
Project: Research project
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RiPP enzyme heterocomplex structure-guided discovery of a bacterial borosin α-N-methylated peptide natural product
Crone, K. K., Jomori, T., Miller, F. S., Gralnick, J. A., Elias, M. H. & Freeman, M. F., Aug 21 2023, In: RSC Chemical Biology. 4, 10, p. 804-816 13 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Diverse Protein Architectures and α- N-Methylation Patterns Define Split Borosin RiPP Biosynthetic Gene Clusters
Imani, A. S., Lee, A. R., Vishwanathan, N., De Waal, F. & Freeman, M. F., Apr 15 2022, In: ACS Chemical Biology. 17, 4, p. 908-917 10 p.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
TaxiBGC: a Taxonomy-Guided Approach for Profiling Experimentally Characterized Microbial Biosynthetic Gene Clusters and Secondary Metabolite Production Potential in Metagenomes
Gupta, V. K., Bakshi, U., Chang, D., Lee, A. R., Davis, J. M., Chandrasekaran, S., Jin, Y. S., Freeman, M. F. & Sung, J., Dec 2022, In: mSystems. 7, 6Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Conformational rearrangements enable iterative backbone N-methylation in RiPP biosynthesis
Miller, F. S., Crone, K. K., Jensen, M. R., Shaw, S., Harcombe, W. R., Elias, M. H. & Freeman, M. F., Dec 1 2021, In: Nature communications. 12, 1, 5355.Research output: Contribution to journal › Article › peer-review
Open Access24 Scopus citations -
Enzyme-mediated backbone N-methylation in ribosomally encoded peptides
Matabaro, E., Song, H., Chepkirui, C., Kaspar, H., Witte, L., Naismith, J. H., Freeman, M. F. & Künzler, M., Jan 2021, Synthetic and Enzymatic Modifications of the Peptide Backbone. Petersson, E. J. (ed.). Academic Press Inc., p. 429-458 30 p. (Methods in Enzymology; vol. 656).Research output: Chapter in Book/Report/Conference proceeding › Chapter
2 Scopus citations