Projects per year
Personal profile
Research interests
For the past decade, I have been involved in medical imaging in humans and more particularly the use of structural and functional magnetic resonance imaging (fMRI) in research and clinical settings. In particular, I have developed tools to better correct motion artifacts in resting-state fMRI (rs-fMRI), studied the reliability of rs-fMRI and applied this modality to study the impact and/or the manifestation of post-traumatic stress disorders on the brains of war veterans and children. In addition, my current research focuses on the improvement of deep brain stimulation (DBS) therapy for movement disorders by using high-resolution MRI at 7 Tesla (T). This work aims at making each aspect of DBS more patient-specific by only focusing our efforts on data coming from a given patient and eliminating the use of templates and group averages. This research encompasses all aspects of DBS after a patient elects to undergo surgery.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Neuroplasticity and the expression of parkinsonian motor signs in idiopathic REM sleep behavior disorder
MacKinnon, C., Amundsen-Huffmaster, S. L., Cooper, S., Eberly, L., Harel, N., Holker, E. G., Howell, M. J. & Patriat, R.
NIH NAT INST OF NEURO DISORDERS & STROKE
8/15/22 → 7/31/25
Project: Research project
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Circuit-based deep brain stimulation for Parkinson's disease
Vitek, J. L., Aman, J. E., Cooper, S., Darrow, D., Escobar Sanabria, D., Hayden, B. Y., Herman, A. B., Holker, E. G., Johnson, L. A., McGovern, R. A., Moeller, S., Netoff, T. I., Park, M. C., Patriat, R., Safo, S., Schrock, L. E., Wang, J., Watson, P. J., Widge, A. S. & Yacoub, E.
NIH NAT INST OF NEURO DISORDERS & STROKE
9/17/21 → 7/31/24
Project: Research project
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7 Tesla functional MRI for Deep Brain Stimulation Targeting
WINSTON & MAXINE WALLIN NEURO DISC FUND
1/1/22 → 12/31/22
Project: Research project
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DiMANI: diffusion MRI for anatomical nuclei imaging—Application for the direct visualization of thalamic subnuclei
Patriat, R., Palnitkar, T., Chandrasekaran, J., Sretavan, K., Braun, H., Yacoub, E., McGovern, R. A., Aman, J., Cooper, S. E., Vitek, J. L. & Harel, N., 2024, In: Frontiers in Human Neuroscience. 18, 1324710.Research output: Contribution to journal › Article › peer-review
Open Access -
Paradoxical Modulation of STN β-Band Activity with Medication Compared to Deep Brain Stimulation
Hill, M. E., Johnson, L. A., Wang, J., Escobar Sanabria, D., Patriat, R., Cooper, S. E., Park, M. C., Harel, N., Vitek, J. L. & Aman, J. E., Jan 2024, In: Movement Disorders. 39, 1, p. 192-197 6 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Active contact proximity to the cerebellothalamic tract predicts initial therapeutic current requirement with DBS for ET: an application of 7T MRI
Ikramuddin, S. S., Brinda, A. K., Butler, R. D., Hill, M. E., Dharnipragada, R., Aman, J. E., Schrock, L. E., Cooper, S. E., Palnitkar, T., Patriat, R., Harel, N., Vitek, J. L. & Johnson, M. D., 2023, In: Frontiers in Neurology. 14, 1258895.Research output: Contribution to journal › Article › peer-review
Open Access -
Lateral cerebellothalamic tract activation underlies DBS therapy for Essential Tremor
Brinda, A. M., Slopsema, J. P., Butler, R. D., Ikramuddin, S., Beall, T., Guo, W., Chu, C., Patriat, R., Braun, H., Goftari, M., Palnitkar, T., Aman, J., Schrock, L., Cooper, S. E., Matsumoto, J., Vitek, J. L., Harel, N. & Johnson, M. D., Mar 1 2023, In: Brain Stimulation. 16, 2, p. 445-455 11 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Low-frequency deep brain stimulation reveals resonant beta-band evoked oscillations in the pallidum of Parkinson’s Disease patients
Zapata Amaya, V., Aman, J. E., Johnson, L. A., Wang, J., Patriat, R., Hill, M. E., MacKinnon, C. D., Cooper, S. E., Darrow, D., McGovern, R., Harel, N., Molnar, G. F., Park, M. C., Vitek, J. L. & Escobar Sanabria, D., 2023, In: Frontiers in Human Neuroscience. 17, 1178527.Research output: Contribution to journal › Article › peer-review
Open Access