Projects per year
Project Details
Description
Abstract:
The overall goal of this NEI Core Center Grant for Vision Research is to enhance the capabilities of vision
research scientists by facilitating easy access to equipment, training and technical support which will expand
experimental capabilities, result in more cost-effective and time-efficient research, and open up new research
directions. This Center will serve vision science researchers across the UT Southwestern Medical Center
(UTSW) campus. It will also facilitate new research collaborations and utilization of the core facilities by vision
scientists at other nearby institutions.
Our proposed NEI Core Center consists of three Resource/Service Modules, each directed by a faculty
member with experience and expertise in their unit’s focus area: 1) Cell Culture and Cell Phenotyping (Directed
by Dr. Danielle Robertson), which will support the maintenance and authentication of cell lines that are
required for rigorous study across a wide range of research activities, and provide equipment and support for
quantitative cellular analysis applications; 2) Molecular Biology/Virus Production (Directed by Dr. John
Hulleman), which will provide full service DNA production and validation as well as lentivirus and adenovirus
production and purification; and, 3) Microscopy and Digital Imaging (Directed by Dr. Matthew Petroll), which
will provide equipment, infra-structural support, supplies and technical assistance for quantitative imaging of
cells and tissues. In addition, the Center includes a biostatistician who will work with Investigators on the
design of their research studies, rigorous analysis of their data, and interpretation of their results.
The Specific Aims of the Core Center are to enhance, streamline and add scientific rigor to the research
activities of the participating vision scientists by: 1) Supporting the operation of the Resource/Service Modules
by managing usage and operations, and providing for skilled technical assistance, equipment maintenance,
and the purchase of supplies; 2) providing biostatistical services to Core investigators for the design and
analysis of their research studies; 3) expanding the number of collaborative research projects between
investigators both within UTSW and between UTSW and other neighboring institutions; 4) creating a more
fertile environment for the development of vision research programs of junior faculty members, and for new
vision researchers recruited into the University; and, 5) providing resources and training to assist graduate
students, medical students, and post-doctoral fellows with their research.
Overall, we anticipate that the Core Grant for Vision Research will impact the research programs of these
researchers by allowing them to: 1) expand into new research areas through the addition of novel experimental
techniques; 2) develop new collaborations with other Core Center users throughout the region; 3) improve their
productivity and efficiency through the use of Core services; and, 4) optimize their experimental design and
analysis to maintain a high level of rigor and reproducibility.
Status | Active |
---|---|
Effective start/end date | 9/30/19 → 6/30/24 |
Fingerprint
Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.
Projects
- 1 Active
-
Molecular Biology/Virus Production
Hulleman, J. D. & Hulleman, J. J. D.
9/1/19 → 6/30/24
Project: Research project