Novel Regulatory Mechanisms of Drosophila Pumilio

Project: Research project

Project Details

Description

PROJECT NARRATIVE This research is relevant to human biology and health because Pumilio proteins are conserved in humans where, like their Drosophila counterpart, they are implicated in control of cell proliferation, fertility and neurological functions. The RNA-binding and Repression Domains of Pumilio are functionally conserved in human Pum orthologs; therefore, our discoveries are expected to be translatable to post-transcriptional regulation of human cancer biology, developmental defects, neurological disorders and infertility.
StatusFinished
Effective start/end date9/20/1312/31/22

Funding

  • National Institute of General Medical Sciences: $289,086.00
  • National Institute of General Medical Sciences: $288,457.00
  • National Institute of General Medical Sciences: $286,915.00
  • National Institute of General Medical Sciences: $286,602.00
  • National Institute of General Medical Sciences: $289,086.00
  • National Institute of General Medical Sciences: $286,658.00
  • National Institute of General Medical Sciences: $321,207.00
  • National Institute of General Medical Sciences: $321,207.00
  • National Institute of General Medical Sciences: $28,640.00
  • National Institute of General Medical Sciences: $258,614.00

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