TY - GEN
T1 - A Multimodalities Comparison of Sensation and Affect in Fibromyalgia Patients and Healthy Controls
T2 - 30th Annual Scientific Meeting of the American Pain Society
AU - Moana-Filho, E. J.
AU - Tchivileva, I. E.
AU - Uraizee, S.
AU - Gracely, R.
N1 - M1 - 4 (Supp)
PY - 2011
Y1 - 2011
N2 - Fibromyalgia (FM) is a chronic pain condition characterized by widespread musculoskeletal pain, tenderness to pressure, and a constellation of symptoms such as fatigue, sleep difficulties, and cognitive dysfunction. Experimental and anecdotal evidence suggests: a) modest correlation between sensitivity to painful heat and pressure; b) influence of the mode of presentation of painful stimuli and c) increased sensory sensitivity is found also for non-painful stimulation, e.g. auditory stimulus. This study addressed these issues and the hypothesis that increased sensitivity to painful and especially non-painful stimuli is due to increased unpleasantness of the evoked sensations. To reduce response biases, 30 FM female patients and 30 age- and sex-matched controls used Gracely Box scales to evaluate sensations evoked by painful heat, painful blunt pressure, and sinusoidal sound stimuli intermingled in the same session. Subjects rated the intensity of the evoked sensations in one session and the unpleasantness in a separate session. Sessions were on separate days (minimum 48 hours) and counterbalanced for order. For each group, subjects were classified as either sensitive or insensitive to each stimulus modality based on the median value for the group medium threshold for that modality. The frequencies of observed sensitivities in the control group were significantly different (P
AB - Fibromyalgia (FM) is a chronic pain condition characterized by widespread musculoskeletal pain, tenderness to pressure, and a constellation of symptoms such as fatigue, sleep difficulties, and cognitive dysfunction. Experimental and anecdotal evidence suggests: a) modest correlation between sensitivity to painful heat and pressure; b) influence of the mode of presentation of painful stimuli and c) increased sensory sensitivity is found also for non-painful stimulation, e.g. auditory stimulus. This study addressed these issues and the hypothesis that increased sensitivity to painful and especially non-painful stimuli is due to increased unpleasantness of the evoked sensations. To reduce response biases, 30 FM female patients and 30 age- and sex-matched controls used Gracely Box scales to evaluate sensations evoked by painful heat, painful blunt pressure, and sinusoidal sound stimuli intermingled in the same session. Subjects rated the intensity of the evoked sensations in one session and the unpleasantness in a separate session. Sessions were on separate days (minimum 48 hours) and counterbalanced for order. For each group, subjects were classified as either sensitive or insensitive to each stimulus modality based on the median value for the group medium threshold for that modality. The frequencies of observed sensitivities in the control group were significantly different (P
U2 - 10.1016/j.jpain.2011.02.173
DO - 10.1016/j.jpain.2011.02.173
M3 - Other contribution
PB - J Pain
CY - Austin, TX. USA.
ER -