A new unusual iridoid with inhibition of Activator Protein-1 (AP-1) from the leaves of Morinda citrifolia L.

Shengmin Sang; Kan He; Guangming Liu; Nanqun Zhu; Xiaofang Cheng; Mingfu Wang; Qunyi Zheng; Zigang Dong; Geetha Ghai; Robert T. Rosen; Chi Tang Ho

doi:10.1021/ol0156648

A new unusual iridoid with inhibition of Activator Protein-1 (AP-1) from the leaves of Morinda citrifolia L.

Shengmin Sang, Kan He, Guangming Liu, Nanqun Zhu, Xiaofang Cheng, Mingfu Wang, Qunyi Zheng, Zigang Dong, Geetha Ghai, Robert T. Rosen, Chi Tang Ho

Hormel Institute

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Abstract

(equation presented) From the leaves of Morinda citrifolia, a new unusual iridoid, named citrifolinoside (1), showing significant inhibition of UVB-induced Activator Protein-1 (AP-1) activity in cell cultures, has been isolated. Its structure was elucidated on the basis of detailed high-field 1D and 2D spectral analysis.

Original language	English (US)
Pages (from-to)	1307-1309
Number of pages	3
Journal	Organic Letters
Volume	3
Issue number	9
DOIs	https://doi.org/10.1021/ol0156648
State	Published - May 3 2001

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title = "A new unusual iridoid with inhibition of Activator Protein-1 (AP-1) from the leaves of Morinda citrifolia L.",

abstract = "(equation presented) From the leaves of Morinda citrifolia, a new unusual iridoid, named citrifolinoside (1), showing significant inhibition of UVB-induced Activator Protein-1 (AP-1) activity in cell cultures, has been isolated. Its structure was elucidated on the basis of detailed high-field 1D and 2D spectral analysis.",

author = "Shengmin Sang and Kan He and Guangming Liu and Nanqun Zhu and Xiaofang Cheng and Mingfu Wang and Qunyi Zheng and Zigang Dong and Geetha Ghai and Rosen, {Robert T.} and Ho, {Chi Tang}",

year = "2001",

month = may,

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language = "English (US)",

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journal = "Organic Letters",

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AU - Sang, Shengmin

AU - He, Kan

AU - Liu, Guangming

AU - Zhu, Nanqun

AU - Cheng, Xiaofang

AU - Wang, Mingfu

AU - Zheng, Qunyi

AU - Dong, Zigang

AU - Ghai, Geetha

AU - Rosen, Robert T.

AU - Ho, Chi Tang

PY - 2001/5/3

Y1 - 2001/5/3

N2 - (equation presented) From the leaves of Morinda citrifolia, a new unusual iridoid, named citrifolinoside (1), showing significant inhibition of UVB-induced Activator Protein-1 (AP-1) activity in cell cultures, has been isolated. Its structure was elucidated on the basis of detailed high-field 1D and 2D spectral analysis.

AB - (equation presented) From the leaves of Morinda citrifolia, a new unusual iridoid, named citrifolinoside (1), showing significant inhibition of UVB-induced Activator Protein-1 (AP-1) activity in cell cultures, has been isolated. Its structure was elucidated on the basis of detailed high-field 1D and 2D spectral analysis.

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A new unusual iridoid with inhibition of Activator Protein-1 (AP-1) from the leaves of Morinda citrifolia L.

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