Antifouling for Electrochemically Biosensing in Body Fluids

Wenzheng He; Changdong Zhou; Yang Lin; Yuxin Tian; Liying Liu; Qifu Zhang; Xiongying Ye; Tianhong Cui

doi:10.1109/MEMS49605.2023.10052511

Antifouling for Electrochemically Biosensing in Body Fluids

Wenzheng He, Changdong Zhou, Yang Lin, Yuxin Tian, Liying Liu, Qifu Zhang, Xiongying Ye, Tianhong Cui

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

1 Scopus citations

Abstract

This paper presents a simple and robust antifouling sensor based on a nano-wrinkle electrode with bovine serum albumin for electrochemically detecting small molecules in complex body fluids. The nano-wrinkle was prepared by a one-step shrinking technique, being capable of excluding large proteins in physical structures and enhancing the response of small molecules. The prepared sensor demonstrates excellent antifouling capability under discontinuous or continuous exposure to proteins or fetal calf serum, which preserves 97% of its original signal after a 21-day exposure to fetal calf serum and enabled the quantification of dopamine in the protein-coexisted environment with a low limit of detection (LOD) (1.09 μM) and a wide detection range from 20 to 1105 μM.

Original language	English (US)
Title of host publication	2023 IEEE 36th International Conference on Micro Electro Mechanical Systems, MEMS 2023
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	285-288
Number of pages	4
ISBN (Electronic)	9781665493086
DOIs	https://doi.org/10.1109/MEMS49605.2023.10052511
State	Published - 2023
Externally published	Yes
Event	36th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2023 - Munich, Germany Duration: Jan 15 2023 → Jan 19 2023

Publication series

Name	Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
Volume	2023-January
ISSN (Print)	1084-6999

Conference

Conference	36th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2023
Country/Territory	Germany
City	Munich
Period	1/15/23 → 1/19/23

Bibliographical note

Publisher Copyright:
© 2023 IEEE.

Keywords

Antifouling
Dopamine
Electrochemical sensor
Nano-wrinkle
Serum
Shrinking technique

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10.1109/MEMS49605.2023.10052511

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He, W., Zhou, C., Lin, Y., Tian, Y., Liu, L., Zhang, Q., Ye, X., & Cui, T. (2023). Antifouling for Electrochemically Biosensing in Body Fluids. In 2023 IEEE 36th International Conference on Micro Electro Mechanical Systems, MEMS 2023 (pp. 285-288). (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS); Vol. 2023-January). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/MEMS49605.2023.10052511

Antifouling for Electrochemically Biosensing in Body Fluids. / He, Wenzheng; Zhou, Changdong; Lin, Yang et al.
2023 IEEE 36th International Conference on Micro Electro Mechanical Systems, MEMS 2023. Institute of Electrical and Electronics Engineers Inc., 2023. p. 285-288 (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS); Vol. 2023-January).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

He, W, Zhou, C, Lin, Y, Tian, Y, Liu, L, Zhang, Q, Ye, X & Cui, T 2023, Antifouling for Electrochemically Biosensing in Body Fluids. in 2023 IEEE 36th International Conference on Micro Electro Mechanical Systems, MEMS 2023. Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS), vol. 2023-January, Institute of Electrical and Electronics Engineers Inc., pp. 285-288, 36th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2023, Munich, Germany, 1/15/23. https://doi.org/10.1109/MEMS49605.2023.10052511

He W, Zhou C, Lin Y, Tian Y, Liu L, Zhang Q et al. Antifouling for Electrochemically Biosensing in Body Fluids. In 2023 IEEE 36th International Conference on Micro Electro Mechanical Systems, MEMS 2023. Institute of Electrical and Electronics Engineers Inc. 2023. p. 285-288. (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)). doi: 10.1109/MEMS49605.2023.10052511

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AU - Ye, Xiongying

AU - Cui, Tianhong

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Antifouling for Electrochemically Biosensing in Body Fluids

Abstract

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