Assessing rTMS effects in MdDS: Cross-modal comparison between resting state EEG and fMRI connectivity

Yafen Chen; Chuang Li; Guofa Shou; Diamond Urbano; Yoon Hee Cha; Lei Ding; Han Yuan

doi:10.1109/EMBC.2017.8037231

Assessing rTMS effects in MdDS: Cross-modal comparison between resting state EEG and fMRI connectivity

Yafen Chen, Chuang Li, Guofa Shou, Diamond Urbano, Yoon Hee Cha, Lei Ding, Han Yuan

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

5 Scopus citations

Abstract

Repetitive transcranial magnetic stimulation (rTMS) has been increasingly explored for many neurological and neuropsychiatric conditions. However, the response rate is variable depending on baseline conditions. Optimizing rTMS protocols to improve treatment effects and response rates will depend on reliably assessing brain state conditions. In this regard, neural activity guided optimization has shown potential in several neuroimaging studies. In this paper, we present our ongoing work on optimizing rTMS treatment of a balance disorder called Mal de Debarquement Syndrome (MdDS), a motion perception disorder caused by entrainment to background motion. Our previous work has revealed that a neuroimaging marker of resting state functional connectivity may help predict therapeutic effect. Motivated by our previous pilot study with fMRI, the present study aims to extend the investigation to EEG data that were simultaneously acquired with fMRI, with the aim of transferring the fMRI imaging marker to a more accessible neural recording technology. Our current findings demonstrate that integrating EEG with fMRI measures of neural synchrony and functional connectivity may hold promise in optimizing rTMS protocols.

Original language	English (US)
Title of host publication	2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Subtitle of host publication	Smarter Technology for a Healthier World, EMBC 2017 - Proceedings
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	1950-1953
Number of pages	4
ISBN (Electronic)	9781509028092
DOIs	https://doi.org/10.1109/EMBC.2017.8037231
State	Published - Sep 13 2017
Externally published	Yes
Event	39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2017 - Jeju Island, Korea, Republic of Duration: Jul 11 2017 → Jul 15 2017

Publication series

Name	Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
ISSN (Print)	1557-170X

Other

Other	39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2017
Country/Territory	Korea, Republic of
City	Jeju Island
Period	7/11/17 → 7/15/17

Bibliographical note

Funding Information:
This work was supported in part by NSF CAREER ECCS-0955260, DOT-FAA 10-G-008, NSF RII Track-2 FEC 1539068, NIH/NIDCD R03 DC010451, and an equipment grant from the MdDS Balance Disorders Foundation. Asterisk indicates corresponding author.

Publisher Copyright:
© 2017 IEEE.

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10.1109/EMBC.2017.8037231

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Chen, Y., Li, C., Shou, G., Urbano, D., Cha, Y. H., Ding, L., & Yuan, H. (2017). Assessing rTMS effects in MdDS: Cross-modal comparison between resting state EEG and fMRI connectivity. In 2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Smarter Technology for a Healthier World, EMBC 2017 - Proceedings (pp. 1950-1953). Article 8037231 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/EMBC.2017.8037231

Assessing rTMS effects in MdDS: Cross-modal comparison between resting state EEG and fMRI connectivity. / Chen, Yafen; Li, Chuang; Shou, Guofa et al.
2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Smarter Technology for a Healthier World, EMBC 2017 - Proceedings. Institute of Electrical and Electronics Engineers Inc., 2017. p. 1950-1953 8037231 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Chen, Y, Li, C, Shou, G, Urbano, D, Cha, YH, Ding, L & Yuan, H 2017, Assessing rTMS effects in MdDS: Cross-modal comparison between resting state EEG and fMRI connectivity. in 2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Smarter Technology for a Healthier World, EMBC 2017 - Proceedings., 8037231, Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, Institute of Electrical and Electronics Engineers Inc., pp. 1950-1953, 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2017, Jeju Island, Korea, Republic of, 7/11/17. https://doi.org/10.1109/EMBC.2017.8037231

Chen Y, Li C, Shou G, Urbano D, Cha YH, Ding L et al. Assessing rTMS effects in MdDS: Cross-modal comparison between resting state EEG and fMRI connectivity. In 2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Smarter Technology for a Healthier World, EMBC 2017 - Proceedings. Institute of Electrical and Electronics Engineers Inc. 2017. p. 1950-1953. 8037231. (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS). doi: 10.1109/EMBC.2017.8037231

Chen, Yafen ; Li, Chuang ; Shou, Guofa et al. / Assessing rTMS effects in MdDS : Cross-modal comparison between resting state EEG and fMRI connectivity. 2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Smarter Technology for a Healthier World, EMBC 2017 - Proceedings. Institute of Electrical and Electronics Engineers Inc., 2017. pp. 1950-1953 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS).

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Assessing rTMS effects in MdDS: Cross-modal comparison between resting state EEG and fMRI connectivity

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