@inproceedings{3ac39aac4ec944b0a06f87223531f181,
title = "Assessing the dynamic biofilm removal of sulfonated phenolics using CP-OCT",
abstract = "Examining the physical mechanisms related to biofilm removal of sulfonated phenolics (SP) is difficult using conventional microscopy techniques. A custom flow cell system integrated with a real time cross polarization optical coherence tomography system investigated the dynamic speed of biofilm removal when oral multi-species biofilms are exposed to SP under sheer stress. The Near infrared 1310-nm CP-OCT system non-destructively imaged fluid immersed oral biofilms at nearly 30 frames/s. This dynamic imaging was able to determine the cohesive and adhesion related disruption of SP on oral biofilms adhering to tooth like surfaces. For multi-species biofilms that are initially grown without the presence of sucrose, the disruption of biofilms on saliva coated hydroxyapatite (HA) is dominated as a adhesive failure at the HA-biofilm interface. For multi-species biofilms that are grown in the presence of sucrose, the disruption is dominated by cohesive disruption followed by adhesive failure. This novel CP-OCT flow cell assay has the potential to examine rapid interactions between anti-biofilm agents and tooth like surfaces.",
keywords = "Biofilm, Biofilm Disruption, Dentistry, Optical Coherence Tomography, Sulfonated Phenolics",
author = "K. Englund and J. Nikrad and Jones, {Robert S}",
year = "2017",
month = jan,
day = "1",
doi = "10.1117/12.2254624",
language = "English (US)",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
publisher = "SPIE",
editor = "Daniel Fried and Peter Rechmann",
booktitle = "Lasers in Dentistry XXIII",
address = "United States",
note = "Lasers in Dentistry XXIII ; Conference date: 29-01-2017",
}