Abstract
The synthesis of optically active α-alkylated azepane-2-carboxylic acid esters 3 was achieved via Schmidt rearrangement of optically active ethyl 2-oxo-1-alkyl-cyclohexanecarboxylates 1 followed by selective reduction of the amide carbonyl group.
Original language | English (US) |
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Pages (from-to) | 125-128 |
Number of pages | 4 |
Journal | Bioorganic and Medicinal Chemistry Letters |
Volume | 1 |
Issue number | 2 |
DOIs | |
State | Published - 1991 |