Abstract
An efficient asymmetric synthesis of (+)-tetrahydropseudodistomin is described. The important synthetic features include a Maruoka asymmetric allylation and a Sharpless asymmetric dihydroxylation as key steps for the generation of chirality at C-2, -4, and -5 of the trisubstituted piperidine ring.
Original language | English (US) |
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Pages (from-to) | 2373-2375 |
Number of pages | 3 |
Journal | Tetrahedron Letters |
Volume | 48 |
Issue number | 13 |
DOIs | |
State | Published - Mar 26 2007 |
Externally published | Yes |
Bibliographical note
Funding Information:S.S.S. thanks the CSIR, New Delhi and N.K. thanks the UGC, New Delhi, for financial support and S.C. thanks the DST, New Delhi, for a grant.
Keywords
- Marouka asymmetric allylation
- Sharpless asymmetric dihydroxylation