TY - JOUR
T1 - Behavioral effects of fluoxetine on aggression and associative learning in Siamese fighting fish (Betta splendens)
AU - Eisenreich, Benjamin R.
AU - Szalda-Petree, Allen
N1 - Publisher Copyright:
© 2015 Elsevier B.V.
PY - 2015/12/1
Y1 - 2015/12/1
N2 - Past research has implicated serotonin as an important neurotransmitter in the facilitation of aggressive behavior. In Siamese fighting fish (Betta splendens), the SSRI fluoxetine has been demonstrated to reduce both frequency and duration of aggressive displays across a variety of concentration exposure procedures. While this multi-method approach has provided strong evidence for fluoxetine's impact on aggression, no study has sought to examine the behavioral mechanism by which fluoxetine exerts its anti-aggressive effect. To address this question, a Go-No Go discrimination task utilizing mirror presentations as a reinforcer was designed. Consistent with previous reports, the results indicated that fluoxetine may exert a sedative effect upon aggressive behavior via decreased arousal to external stimuli.
AB - Past research has implicated serotonin as an important neurotransmitter in the facilitation of aggressive behavior. In Siamese fighting fish (Betta splendens), the SSRI fluoxetine has been demonstrated to reduce both frequency and duration of aggressive displays across a variety of concentration exposure procedures. While this multi-method approach has provided strong evidence for fluoxetine's impact on aggression, no study has sought to examine the behavioral mechanism by which fluoxetine exerts its anti-aggressive effect. To address this question, a Go-No Go discrimination task utilizing mirror presentations as a reinforcer was designed. Consistent with previous reports, the results indicated that fluoxetine may exert a sedative effect upon aggressive behavior via decreased arousal to external stimuli.
KW - Aggression
KW - Fluoxetine
KW - Learning
KW - Motivation
KW - Serotonin
UR - http://www.scopus.com/inward/record.url?scp=84945261868&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84945261868&partnerID=8YFLogxK
U2 - 10.1016/j.beproc.2015.10.008
DO - 10.1016/j.beproc.2015.10.008
M3 - Article
C2 - 26478253
AN - SCOPUS:84945261868
SN - 0376-6357
VL - 121
SP - 37
EP - 42
JO - Behavioural Processes
JF - Behavioural Processes
ER -