Biology of bone cancer pain

Patrick W. O’Donnell; Denis R. Clohisy

doi:10.1007/978-1-4614-5662-9_3

Biology of bone cancer pain

Patrick W. O’Donnell, Denis R. Clohisy

Orthopaedic Surgery

Research output: Chapter in Book/Report/Conference proceeding › Chapter

4 Scopus citations

Abstract

Bone cancer pain is a complex process with many potential targets for therapeutic intervention. As pain is the most common presenting symptom in patients with skeletal metastases and is directly proportional to the patient’s quality of life, clinical advancements in the treatment of bone cancer pain are of the utmost importance. Research targeting pain-related cytokines, anti-osteoclastic medications, and ion channels has shown significant clinical progress in the treatment of cancer-related bone pain. With continued efforts into these and other therapeutic strategies, we hope to continue to improve the quality of life of those patients suffering with bone cancer pain.

Original language	English (US)
Title of host publication	Metastatic Bone Disease
Subtitle of host publication	An Integrated Approach to Patient Care
Publisher	Springer New York
Pages	37-44
Number of pages	8
ISBN (Electronic)	9781461456629
ISBN (Print)	9781461456612
DOIs	https://doi.org/10.1007/978-1-4614-5662-9_3
State	Published - Jan 1 2015

Bibliographical note

Publisher Copyright:
© Springer Science+Business Media New York 2016.

Keywords

Bisphosphonates
Bone cancer
Denosumab
Ion channels
Osteoclast
Pain
Skeletal metastasis

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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KW - Ion channels

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Biology of bone cancer pain

Abstract

Bibliographical note

Keywords

UN SDGs

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