Case of Primary Hepatic Angiosarcoma Presenting With Jaundice and Infiltrative Liver Masses

Adnan Shaaban; Chimaobi Anugwom; Alma Habib; Tetyana Mettler; Shahid Jaffer; Mary Thomson

doi:10.1177/23247096221111768

Case of Primary Hepatic Angiosarcoma Presenting With Jaundice and Infiltrative Liver Masses

Adnan Shaaban, Chimaobi Anugwom, Alma Habib, Tetyana Mettler, Shahid Jaffer, Mary Thomson

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Abstract

Primary hepatic angiosarcoma (PHA) is a rare and aggressive mesenchymal liver tumor with a poor prognosis and high mortality. Treatment options are limited to palliative chemotherapy with surgical resection reserved for the few cases that present early. We present a case of a patient who presented with jaundice and elevated liver enzymes. Imaging identified a diffusely heterogeneous liver consistent with cirrhosis, findings of portal hypertension, and 2 ill-defined liver lesions. Biopsy results confirmed PHA. Primary hepatic angiosarcoma does not have a typical presentation but should be considered for any patient presenting with an infiltrative liver mass.

Original language	English (US)
Journal	Journal of Investigative Medicine High Impact Case Reports
Volume	10
DOIs	https://doi.org/10.1177/23247096221111768
State	Published - 2022

Bibliographical note

Publisher Copyright:
© 2022 American Federation for Medical Research.

Keywords

abnormal liver enzymes
hepatic angiosarcoma
malignant liver tumor
mortality

PubMed: MeSH publication types

Case Reports
Journal Article

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title = "Case of Primary Hepatic Angiosarcoma Presenting With Jaundice and Infiltrative Liver Masses",

abstract = "Primary hepatic angiosarcoma (PHA) is a rare and aggressive mesenchymal liver tumor with a poor prognosis and high mortality. Treatment options are limited to palliative chemotherapy with surgical resection reserved for the few cases that present early. We present a case of a patient who presented with jaundice and elevated liver enzymes. Imaging identified a diffusely heterogeneous liver consistent with cirrhosis, findings of portal hypertension, and 2 ill-defined liver lesions. Biopsy results confirmed PHA. Primary hepatic angiosarcoma does not have a typical presentation but should be considered for any patient presenting with an infiltrative liver mass.",

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AU - Habib, Alma

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AU - Jaffer, Shahid

AU - Thomson, Mary

PY - 2022

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N2 - Primary hepatic angiosarcoma (PHA) is a rare and aggressive mesenchymal liver tumor with a poor prognosis and high mortality. Treatment options are limited to palliative chemotherapy with surgical resection reserved for the few cases that present early. We present a case of a patient who presented with jaundice and elevated liver enzymes. Imaging identified a diffusely heterogeneous liver consistent with cirrhosis, findings of portal hypertension, and 2 ill-defined liver lesions. Biopsy results confirmed PHA. Primary hepatic angiosarcoma does not have a typical presentation but should be considered for any patient presenting with an infiltrative liver mass.

AB - Primary hepatic angiosarcoma (PHA) is a rare and aggressive mesenchymal liver tumor with a poor prognosis and high mortality. Treatment options are limited to palliative chemotherapy with surgical resection reserved for the few cases that present early. We present a case of a patient who presented with jaundice and elevated liver enzymes. Imaging identified a diffusely heterogeneous liver consistent with cirrhosis, findings of portal hypertension, and 2 ill-defined liver lesions. Biopsy results confirmed PHA. Primary hepatic angiosarcoma does not have a typical presentation but should be considered for any patient presenting with an infiltrative liver mass.

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KW - malignant liver tumor

KW - mortality

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Case of Primary Hepatic Angiosarcoma Presenting With Jaundice and Infiltrative Liver Masses

Abstract

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