Cell type‐dependence for Vpu function

Robert J. Geraghty, Katrin J. Talbot, Michael Callahan, Wade Harper, Antonito T. Panganiban

Research output: Contribution to journalArticlepeer-review

47 Scopus citations

Abstract

Human immunodeficiency virus type 1 Vpu has been shown to facilitate virus release from HeLa cells. We demonstrated that Vpu expression is not required for efficient virus release from Cos 1 and CV‐1 cells. A yeast GAL4 transcriptional activation system was used to screen for cellular proteins that may interact with Vpu. One such protein was identified which we provisionally designate “Vpu interactive protein” or VIP. 1994 Munksgaard

Original languageEnglish (US)
Pages (from-to)146-150
Number of pages5
JournalJournal of Medical Primatology
Volume23
Issue number2-3
DOIs
StatePublished - 1994
Externally publishedYes

Keywords

  • fusion protein
  • retrovirus
  • virus release
  • yeast

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