Projects per year
Abstract
Here, we investigate the impact of iron oxide nanoparticles (IONPs) and mesoporous silica-coated iron oxide nanoparticles (msIONPs) on Shewanella oneidensis in an aerobic environment, which is likely the main environment where such nanoparticles will end up after use in consumer products or biomedical applications. Monitoring the viability of S. oneidensis, a model environmental organism, after exposure to the nanoparticles reveals that IONPs promote bacterial survival, while msIONPs do not impact survival. These apparent impacts are correlated with association of the nanoparticles with the bacterial membrane, as revealed by TEM and ICP-MS studies, and upregulation of membrane-associated genes. However, similar survival in bacteria was observed when exposed to equivalent concentrations of released ions from each nanomaterial, indicating that aqueous nanoparticle transformations are responsible for the observed changes in bacterial viability. Therefore, this work demonstrates that a simple mesoporous silica coating can control the dissolution of the IONP core by greatly reducing the amount of released iron ions, making msIONPs a more sustainable option to reduce perturbations to the ecosystem upon release of nanoparticles into the environment.
Original language | English (US) |
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Article number | 124511 |
Journal | Chemosphere |
Volume | 237 |
DOIs | |
State | Published - Dec 2019 |
Bibliographical note
Publisher Copyright:© 2019 Elsevier Ltd
Keywords
- Bacteria
- Dissolution
- Gene expression
- Iron oxide
- Nanotoxicity
- Silica
How much support was provided by MRSEC?
- Shared
Reporting period for MRSEC
- Period 6
PubMed: MeSH publication types
- Journal Article
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MRSEC IRG-2: Sustainable Nanocrystal Materials
Kortshagen, U. R., Aydil, E. S., Campbell, S. A., Francis, L. F., Haynes, C. L., Hogan, C., Mkhoyan, A., Shklovskii, B. I. & Wang, X.
9/1/98 → …
Project: Research project
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MRSEC Program
THE NATIONAL SCIENCE FOUNDATION, UNIVERSITY OF TEXAS RIO GRANDE VALLEY
8/1/98 → 10/31/20
Project: Research project