Cochlear turns measurements in patients with meningitis: A histopathological study

Henrique F. Pauna, Michael M. Paparella, Sebahattin Cureoglu, Miguel A. Hyppolito

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Objective: To demonstrate the cochlear turns area changes among patients with a history of meningitis, through otopatologic study. Methods: We performed an analysis of the area of the bony cochlear turns and the cochlear lumen of the horizontal sections containing the modiolus and the area of the basal turn at the level of round window, in temporal bones obtained from patients with a history of meningitis and compared to a nondiseased control group. Results: The mean area of the bony walls and the lumen of all cochlear turns are reduced within the meningitis group. Patients who presented a time from the diagnosis of meningitis to death longer than 30 days had a significant reduction in the cochlear turns area, as compared to the control group. Conclusion: Future studies may further correlate audiologic outcomes, cochlear volume, and cochlear area among patients with meningitis.

Original languageEnglish (US)
Pages (from-to)506-510
Number of pages5
JournalLaryngoscope investigative otolaryngology
Volume5
Issue number3
DOIs
StatePublished - Jun 1 2020

Bibliographical note

Funding Information:
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, Grant/Award Number: CAPES code 001; International Hearing Foundation; Lions 5M International; National Institute on Deafness and Other Communication Disorders, Grant/Award Number: U24 DC011968; Starkey Hearing Foundation

Publisher Copyright:
© 2020 The Authors. Laryngoscope Investigative Otolaryngology published by Wiley Periodicals, Inc. on behalf of The Triological Society.

Keywords

  • cochlear turns
  • labyrinthitis ossificans
  • meningitis
  • otopathology
  • temporal bone

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