Abstract
Animal models are essential for studying disease pathogenesis and to test the efficacy and safety of new vaccines and therapeutics. For most diseases, there is no single model that can recapitulate all features of the human condition, so it is vital to understand the advantages and disadvantages of each. The purpose of this review is to describe popular comparative animal models, including mice, ferrets, hamsters, and non-human primates (NHPs), that are being used to study clinical and pathological changes caused by influenza A virus infection with the aim to aid in appropriate model selection for disease modeling.
| Original language | English (US) |
|---|---|
| Article number | 35 |
| Journal | Pathogens |
| Volume | 13 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 2024 |
Bibliographical note
Publisher Copyright:© 2023 by the authors.
Keywords
- animal models
- IAV
- IBV
- influenza virus
- pathogenesis
- pathology
- respiratory pathogens
PubMed: MeSH publication types
- Journal Article
- Review
