Comparison of measures of functioning for use with treatment-seeking adolescents experiencing attenuated symptoms of psychosis

Aim: A growing body of research documents a relation between psychosis risk and functional impairment. Although a general picture of psychosis risk and impaired functioning is emerging, less is known about how different functional measures relate to specific psychosis-risk symptoms. Methods: The current study examines the relative contribution of psychosis-risk symptoms across multiple measures of functioning in a sample of treatment-seeking adolescents and young adults. Results: Results indicate that different domains of psychosis-risk symptoms (negative and positive psychotic symptoms, related affective symptoms) contribute differentially to measures of different types of functioning. Conclusion: Study of the relation between psychosis-risk symptoms and different measures of functional impairment can potentially contribute towards a more efficient use of measures of functioning and help inform individualized treatment considerations.