Current therapy for recurrent and extensive anal warts

PURPOSE: This study was undertaken to review the literature regarding the current therapy for recurrent and extensive anal warts. METHODS: The available treatments for condyloma acuminatum are reviewed with particular regard to their efficacy for recurrent or extensive anal lesions. Topical agents, surgical methods, and the use of interferon are discussed. Treatment of anal warts in the immunocompromised patient is also addressed. CONCLUSIONS: Although small lesions may be responsive to repeated applications of topical agents, more extensive lesions require surgical or combination treatment. Intralesional interferon may be a useful adjunct to surgical methods to decrease recurrence.