Discovery of a Substrate Selectivity Switch in Tyrosine Ammonia-Lyase, a Member of the Aromatic Amino Acid Lyase Family

Medicine & Life Sciences

• L-tyrosine ammonia-lyase 100%
• Lyases 68%
• Aromatic Amino Acids 68%
• Phenylalanine 52%
• Substrate Specificity 26%
• Tyrosine 22%
• Histidine Ammonia-Lyase 21%
• Catalytic Domain 21%
• Phenylalanine Ammonia-Lyase 21%
• trans-3-(4'-hydroxyphenyl)-2-propenoic acid 19%
• Enzymes 13%
• Point Mutation 11%
• Amino Acids 8%
• Genome 8%
• Anti-Bacterial Agents 7%
• Mutation 6%
• Proteins 4%

Chemical Compounds

• Aromatic Amino Acid 55%
• Phenylalanine 48%
• Tyrosine 43%
• 4-Coumaric Acid 17%
• Mutation 16%
• L-Tyrosine 12%
• Histidine 9%
• Cofactor 8%
• Antimicrobial Agent 6%
• Protein 3%
• Acid 3%