Donor‐specific transfusion via the portal venous route induces prolongation of H‐2‐compatible but not H‐2‐incompatible cardiac graft survival

D. Górecki; M. Jakóbisiak; M. Lupińska; A. Kruszewski; J. Czyńyk

doi:10.1111/j.1432-2277.1989.tb01866.x

Donor‐specific transfusion via the portal venous route induces prolongation of H‐2‐compatible but not H‐2‐incompatible cardiac graft survival

D. Górecki, M. Jakóbisiak, M. Lupińska, A. Kruszewski, J. Czyńyk

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Abstract

Abstract. In the H‐2‐compatible donor‐recipient combination (BALB/c ± DBA/2), pretransplant donor‐specific blood transfusion (DST) via the portal venous (PV) route significantly prolonged cardiac graft survival. DST via the intravenous (IV) route (systemic circulation) also showed a marked prolongation of heart tissue transplant survival in this model. In the H‐2‐incompatible combination (BALB/c → CBA/H), DST via the IV ‐ but not via the PV ‐ route resulted in accelerated graft rejection.

Original language	English (US)
Pages (from-to)	199-202
Number of pages	4
Journal	Transplant International
Volume	2
Issue number	1
DOIs	https://doi.org/10.1111/j.1432-2277.1989.tb01866.x
State	Published - Jan 1989
Externally published	Yes

Keywords

Transfusion effect
experimental
experimental ‐ Portal venous route
heart ‐ Heart transplantation
intraportal route ‐ Transfusion effect
transfusion effect

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abstract = "Abstract. In the H‐2‐compatible donor‐recipient combination (BALB/c ± DBA/2), pretransplant donor‐specific blood transfusion (DST) via the portal venous (PV) route significantly prolonged cardiac graft survival. DST via the intravenous (IV) route (systemic circulation) also showed a marked prolongation of heart tissue transplant survival in this model. In the H‐2‐incompatible combination (BALB/c → CBA/H), DST via the IV ‐ but not via the PV ‐ route resulted in accelerated graft rejection.",

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AU - Górecki, D.

AU - Jakóbisiak, M.

AU - Lupińska, M.

AU - Kruszewski, A.

AU - Czyńyk, J.

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AB - Abstract. In the H‐2‐compatible donor‐recipient combination (BALB/c ± DBA/2), pretransplant donor‐specific blood transfusion (DST) via the portal venous (PV) route significantly prolonged cardiac graft survival. DST via the intravenous (IV) route (systemic circulation) also showed a marked prolongation of heart tissue transplant survival in this model. In the H‐2‐incompatible combination (BALB/c → CBA/H), DST via the IV ‐ but not via the PV ‐ route resulted in accelerated graft rejection.

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KW - heart ‐ Heart transplantation

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Donor‐specific transfusion via the portal venous route induces prolongation of H‐2‐compatible but not H‐2‐incompatible cardiac graft survival

Abstract

Keywords

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