Dynorphin: A possible modulatory peptide on morphine or β-endorphin analgesia in mouse

Howard J. Friedman; Ming Feng Jen; Jaw Kang Chang; Nancy M. Lee; Horace H. Loh

doi:10.1016/0014-2999(81)90483-0

Dynorphin: A possible modulatory peptide on morphine or β-endorphin analgesia in mouse

Howard J. Friedman, Ming Feng Jen, Jaw Kang Chang, Nancy M. Lee, Horace H. Loh

Pharmacology

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130 Scopus citations

Abstract

Dynorphin-(1-13), but not dynorphin-(1-9) has been shown to have significant effects on opiate and β-endorphin-induced analgesia despite not having any appreciable analgesic activity itself. Dynorphin had no effect on Sandoz FK33824 compound-induced analgesia.

Original language	English (US)
Pages (from-to)	357-360
Number of pages	4
Journal	European Journal of Pharmacology
Volume	69
Issue number	3
DOIs	https://doi.org/10.1016/0014-2999(81)90483-0
State	Published - Jan 29 1981

Keywords

Analgesia
Dynorphin
Morphine
β-Endorphin

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abstract = "Dynorphin-(1-13), but not dynorphin-(1-9) has been shown to have significant effects on opiate and β-endorphin-induced analgesia despite not having any appreciable analgesic activity itself. Dynorphin had no effect on Sandoz FK33824 compound-induced analgesia.",

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AU - Friedman, Howard J.

AU - Jen, Ming Feng

AU - Chang, Jaw Kang

AU - Lee, Nancy M.

AU - Loh, Horace H.

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AB - Dynorphin-(1-13), but not dynorphin-(1-9) has been shown to have significant effects on opiate and β-endorphin-induced analgesia despite not having any appreciable analgesic activity itself. Dynorphin had no effect on Sandoz FK33824 compound-induced analgesia.

KW - Analgesia

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KW - Morphine

KW - β-Endorphin

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Dynorphin: A possible modulatory peptide on morphine or β-endorphin analgesia in mouse

Abstract

Keywords

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