Effect of clindamycin on pneumonia from reactivation of Toxoplasma gondii infection in mice

G. A. Filice, C. Pomeroy

Research output: Contribution to journalArticlepeer-review

15 Scopus citations

Abstract

Clindamycin was used to treat the reactivation of a chronic Toxoplasma gondii infection in mice. Clindamycin reduced mortality by 44% when used prophylactically (P < 0.001) but appeared to be less effective when used to treat clinically apparent reactivation. Further studies should be conducted to establish the efficacy of clindamycin for the treatment of toxoplasmosis in humans.

Original languageEnglish (US)
Pages (from-to)780-782
Number of pages3
JournalAntimicrobial agents and chemotherapy
Volume35
Issue number4
DOIs
StatePublished - 1991

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