Effect of tissue ultrafiltration on skin flap survival

Rick M. Odland; Daryl Rheuark; Scott Ispirescu; Ron Kizziar

doi:10.1016/j.otohns.2004.03.005

Effect of tissue ultrafiltration on skin flap survival

Rick M. Odland, Daryl Rheuark, Scott Ispirescu, Ron Kizziar

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Objective Tissue ultrafiltration (TUF) is a method of reducing tissue edema by removal of interstitial fluid. Considering the deleterious effects of edema on microcirculation and tissue viability, the effect of TUF on skin flap survival was tested. Study design and setting Survival of modified McFarlane skin flaps was determined in 40 Sprague-Dawley rats. In 20 treated animals, four 5-cm ultrafiltration catheters were placed in the subdermal plane of the distal flap 24 hours after flap elevation and connected to a down-regulated vacuum manifold for 8 hours. No catheters were placed in the control group. Results Skin flap survival was improved in the experimental group (87.2 ±1.6) over the control group (76.7±2.2). Discussion TUF effectively improved skin flap survival. These results provide evidence of the causal effect of edema on tissue viability. The relative ease of use of TUF would allow cost-effective clinical application of this technique.

Original language	English (US)
Pages (from-to)	296-299
Number of pages	4
Journal	Otolaryngology - Head and Neck Surgery
Volume	131
Issue number	3
DOIs	https://doi.org/10.1016/j.otohns.2004.03.005
State	Published - Sep 2004
Externally published	Yes

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title = "Effect of tissue ultrafiltration on skin flap survival",

abstract = "Objective Tissue ultrafiltration (TUF) is a method of reducing tissue edema by removal of interstitial fluid. Considering the deleterious effects of edema on microcirculation and tissue viability, the effect of TUF on skin flap survival was tested. Study design and setting Survival of modified McFarlane skin flaps was determined in 40 Sprague-Dawley rats. In 20 treated animals, four 5-cm ultrafiltration catheters were placed in the subdermal plane of the distal flap 24 hours after flap elevation and connected to a down-regulated vacuum manifold for 8 hours. No catheters were placed in the control group. Results Skin flap survival was improved in the experimental group (87.2 ±1.6) over the control group (76.7±2.2). Discussion TUF effectively improved skin flap survival. These results provide evidence of the causal effect of edema on tissue viability. The relative ease of use of TUF would allow cost-effective clinical application of this technique.",

author = "Odland, {Rick M.} and Daryl Rheuark and Scott Ispirescu and Ron Kizziar",

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AU - Rheuark, Daryl

AU - Ispirescu, Scott

AU - Kizziar, Ron

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N2 - Objective Tissue ultrafiltration (TUF) is a method of reducing tissue edema by removal of interstitial fluid. Considering the deleterious effects of edema on microcirculation and tissue viability, the effect of TUF on skin flap survival was tested. Study design and setting Survival of modified McFarlane skin flaps was determined in 40 Sprague-Dawley rats. In 20 treated animals, four 5-cm ultrafiltration catheters were placed in the subdermal plane of the distal flap 24 hours after flap elevation and connected to a down-regulated vacuum manifold for 8 hours. No catheters were placed in the control group. Results Skin flap survival was improved in the experimental group (87.2 ±1.6) over the control group (76.7±2.2). Discussion TUF effectively improved skin flap survival. These results provide evidence of the causal effect of edema on tissue viability. The relative ease of use of TUF would allow cost-effective clinical application of this technique.

AB - Objective Tissue ultrafiltration (TUF) is a method of reducing tissue edema by removal of interstitial fluid. Considering the deleterious effects of edema on microcirculation and tissue viability, the effect of TUF on skin flap survival was tested. Study design and setting Survival of modified McFarlane skin flaps was determined in 40 Sprague-Dawley rats. In 20 treated animals, four 5-cm ultrafiltration catheters were placed in the subdermal plane of the distal flap 24 hours after flap elevation and connected to a down-regulated vacuum manifold for 8 hours. No catheters were placed in the control group. Results Skin flap survival was improved in the experimental group (87.2 ±1.6) over the control group (76.7±2.2). Discussion TUF effectively improved skin flap survival. These results provide evidence of the causal effect of edema on tissue viability. The relative ease of use of TUF would allow cost-effective clinical application of this technique.

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Effect of tissue ultrafiltration on skin flap survival

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