Abstract
Animal models are a critical tool in modern biology. To increase reproducibility and to reduce confounding variables modern animal models exclude many microbes, including key natural commensals and pathogens. Here we discuss recent strategies to incorporate a natural microbiota to laboratory mouse models and the impacts the microbiota has on immune responses, with a focus on viruses.
Original language | English (US) |
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Article number | 001758 |
Journal | Journal of General Virology |
Volume | 103 |
Issue number | 6 |
DOIs | |
State | Published - 2022 |
Bibliographical note
Publisher Copyright:© 2022 Microbiology Society. All rights reserved.
Keywords
- dirty mice
- microbiome
- virome