Enhanced Performance of Blended Polymer Excipients in Delivering a Hydrophobic Drug through the Synergistic Action of Micelles and HPMCAS

Chemical Compounds

• Hydroxypropyl Methylcellulose 92%
• Phenytoin 89%
• Supersaturation 76%
• Excipient 72%
• Succinate 69%
• Micelle 51%
• Dissolution 49%
• Acetate 46%
• Drug 35%
• Poly(N-Isopropylacrylamide) Polymer 34%
• Crystal Nucleation 30%
• Nuclear Overhauser Effect 26%
• Isopropyl Group 25%
• Polarized Light 25%
• Cryogenics 24%
• Association Constant 22%
• Phenyl Group 22%
• Crystal Growth 21%
• Light Scattering 20%
• Intermolecular Force 19%
• Diffusion Coefficient 19%
• Crystallization 15%
• NMR Spectroscopy 14%
• Transmission Electron Microscopy 14%
• Weight 11%
• Reduction 10%
• pH Value 9%

Physics & Astronomy

• micelles 72%
• acetates 71%
• drugs 66%
• supersaturation 44%
• polymers 38%
• dissolving 36%
• performance 29%
• Overhauser effect 19%
• light transmission 15%
• polymer blends 15%
• versatility 14%
• phenyls 14%
• ingredients 13%
• phosphates 13%
• coronas 13%
• polarized light 12%
• molecular weight 12%
• polymerization 12%
• cryogenics 12%
• fragmentation 11%
• light scattering 11%
• diffusion coefficient 10%
• nuclear magnetic resonance 10%
• crystallization 10%
• retarding 10%
• nucleation 9%
• transmission electron microscopy 8%
• spectroscopy 6%
• crystals 6%
• interactions 5%

Engineering & Materials Science

• Micelles 100%
• Supersaturation 73%
• Dissolution 52%
• Polymers 48%
• Nuclear magnetic resonance spectroscopy 25%
• Light polarization 24%
• Light scattering 23%
• Polymer blends 23%
• Light transmission 21%
• Phosphates 18%
• Molecular weight 18%
• Polymerization 18%
• Crystallization 17%
• Cryogenics 17%
• Nucleation 17%
• Transmission electron microscopy 16%
• Crystals 16%
• Experiments 5%