Epstein-Barr virus and host cell 3D genome organization

Chong Wang; Bo Zhao

doi:10.1002/jmv.29234

Epstein-Barr virus and host cell 3D genome organization

Chong Wang, Bo Zhao

Basic Sciences

Research output: Contribution to journal › Review article › peer-review

Abstract

The human genome is organized in an extremely complexed yet ordered way within the nucleus. Genome organization plays a critical role in the regulation of gene expression. Viruses manipulate the host machinery to influence host genome organization to favor their survival and promote disease development. Epstein-Barr virus (EBV) is a common human virus, whose infection is associated with various diseases, including infectious mononucleosis, cancer, and autoimmune disorders. This review summarizes our current knowledge of how EBV uses different strategies to control the cellular 3D genome organization to affect cell gene expression to transform normal cells into lymphoblasts.

Original language	English (US)
Article number	e29234
Journal	Journal of Medical Virology
Volume	95
Issue number	11
DOIs	https://doi.org/10.1002/jmv.29234
State	Published - Nov 2023

Bibliographical note

Publisher Copyright:
© 2023 The Authors. Journal of Medical Virology published by Wiley Periodicals LLC.

Keywords

3D genome organization
EBV

PubMed: MeSH publication types

Journal Article
Review
Research Support, N.I.H., Extramural

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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Epstein-Barr virus and host cell 3D genome organization

Abstract

Bibliographical note

Keywords

PubMed: MeSH publication types

UN SDGs

Access

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