Evidence that mitogenic lectins induce changes in lymphocyte membrane fluidity

Ronald E. Barnett; Robert E. Scott; Leo T. Furcht; John H. Kersey

doi:10.1038/249465a0

Evidence that mitogenic lectins induce changes in lymphocyte membrane fluidity

Ronald E. Barnett, Robert E. Scott, Leo T. Furcht, John H. Kersey

Laboratory Medicine and Pathology

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Abstract

MITOGENIC plant lectins, such as phytohaemagglutinin (PHA) and concanavalin A (con A), are useful tools to study the control of cell proliferation in lymphocytes. Recent evidence suggests that these mitogenic lectins trigger mitogenesis at the cell membrane^1,2. It is likely that an understanding of the mechanisms by which these lectins stimulate lymphocytes will provide important clues to more general problems of the regulation of proliferation in eukaryotic cells.

Original language	English (US)
Pages (from-to)	465-466
Number of pages	2
Journal	Nature
Volume	249
Issue number	5456
DOIs	https://doi.org/10.1038/249465a0
State	Published - 1974

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title = "Evidence that mitogenic lectins induce changes in lymphocyte membrane fluidity",

abstract = "MITOGENIC plant lectins, such as phytohaemagglutinin (PHA) and concanavalin A (con A), are useful tools to study the control of cell proliferation in lymphocytes. Recent evidence suggests that these mitogenic lectins trigger mitogenesis at the cell membrane1,2. It is likely that an understanding of the mechanisms by which these lectins stimulate lymphocytes will provide important clues to more general problems of the regulation of proliferation in eukaryotic cells.",

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Evidence that mitogenic lectins induce changes in lymphocyte membrane fluidity

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