Evolution of DNA and RNA as catalysts for chemical reactions

Andres Jäschke; Burckhard Seelig

doi:10.1016/S1367-5931(00)00086-7

Evolution of DNA and RNA as catalysts for chemical reactions

Andres Jäschke, Burckhard Seelig

Biochemistry, Molecular Biology, and Biophysics (CBS)

Research output: Contribution to journal › Review article › peer-review

48 Scopus citations

Abstract

In vitro selection from combinatorial nucleic acid libraries has provided new RNA and DNA molecules that have catalytic properties. Catalyzed reactions now go far beyond self-modifying reactions of nucleic acid molecules. The future application of in vitro selected RNA and DNA catalysts in bioorganic synthesis appears promising.

Original language	English (US)
Pages (from-to)	257-262
Number of pages	6
Journal	Current opinion in chemical biology
Volume	4
Issue number	3
DOIs	https://doi.org/10.1016/S1367-5931(00)00086-7
State	Published - Jun 1 2000

Bibliographical note

Funding Information:
Work in the author’s laboratory is supported by the Deutsche Forschungsgemeinschaft (DFG) and by the Bundesministerium für Bildung und Forschung (BMBF).

Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.

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title = "Evolution of DNA and RNA as catalysts for chemical reactions",

abstract = "In vitro selection from combinatorial nucleic acid libraries has provided new RNA and DNA molecules that have catalytic properties. Catalyzed reactions now go far beyond self-modifying reactions of nucleic acid molecules. The future application of in vitro selected RNA and DNA catalysts in bioorganic synthesis appears promising.",

author = "Andres J{\"a}schke and Burckhard Seelig",

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AU - Seelig, Burckhard

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Evolution of DNA and RNA as catalysts for chemical reactions

Abstract

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