TY - JOUR
T1 - Factors impacting bowel symptoms in a contemporary spinal cord injury cohort
T2 - results from the Neurogenic Bladder Research Group Registry
AU - Stoffel, John T.
AU - Barboglio-Romo, Paholo
AU - Lenherr, Sara M.
AU - Elliott, Sean P.
AU - O’Dell, Diana
AU - Myers, Jeremy B.
AU - Welk, Blayne
N1 - Publisher Copyright:
© 2021, The Author(s), under exclusive licence to International Spinal Cord Society.
PY - 2021/9
Y1 - 2021/9
N2 - Study design: Cross sectional. Objectives: To identify variables associated with severe bowel symptoms in spinal cord injured people. Setting: National cohort. Methods: Adult spinal cord injured (SCI) people were recruited for an online registry and 1373 were included for analysis. Univariate analysis and logistic regression was used to evaluate associations between severity of bowel symptoms and variables. Bowel symptoms were assessed by the Neurogenic Bowel Dysfunction (NBD) score and patients scoring ≥14 were categorized as having severe bowel symptoms. Autonomic dysreflexia (AD) severity was measured using a six item questionnaire and reported as total AD score (0–24). Bladder management was categorized as: voiding, clean intermittent catheterization (CIC), surgery (augmentation/diversion) or indwelling catheter. Results: Severe bowel symptoms were reported in 570 (42%) On multivariable logistic regression, every point increase of AD total score was associated with 5% increased odds of having more severe bowel symptoms [OR 1.05 95% CI 1.03–1.10]. Type of bladder management was also associated with more severe symptoms (p = 0.0001). SCI people with indwelling catheters (OR = 2.16, 95% CI 1.40–3.32) or reconstructive surgery (OR = 1.79, 95% CI 1.08–3.32) were almost twice as likely to report more severe bowel symptoms than those performing CIC.
AB - Study design: Cross sectional. Objectives: To identify variables associated with severe bowel symptoms in spinal cord injured people. Setting: National cohort. Methods: Adult spinal cord injured (SCI) people were recruited for an online registry and 1373 were included for analysis. Univariate analysis and logistic regression was used to evaluate associations between severity of bowel symptoms and variables. Bowel symptoms were assessed by the Neurogenic Bowel Dysfunction (NBD) score and patients scoring ≥14 were categorized as having severe bowel symptoms. Autonomic dysreflexia (AD) severity was measured using a six item questionnaire and reported as total AD score (0–24). Bladder management was categorized as: voiding, clean intermittent catheterization (CIC), surgery (augmentation/diversion) or indwelling catheter. Results: Severe bowel symptoms were reported in 570 (42%) On multivariable logistic regression, every point increase of AD total score was associated with 5% increased odds of having more severe bowel symptoms [OR 1.05 95% CI 1.03–1.10]. Type of bladder management was also associated with more severe symptoms (p = 0.0001). SCI people with indwelling catheters (OR = 2.16, 95% CI 1.40–3.32) or reconstructive surgery (OR = 1.79, 95% CI 1.08–3.32) were almost twice as likely to report more severe bowel symptoms than those performing CIC.
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U2 - 10.1038/s41393-021-00667-9
DO - 10.1038/s41393-021-00667-9
M3 - Article
C2 - 34345004
AN - SCOPUS:85111867243
SN - 1362-4393
VL - 59
SP - 997
EP - 1002
JO - Spinal Cord
JF - Spinal Cord
IS - 9
ER -