Fe3+-Doped Aminated Lignin as Peroxidase-Mimicking Nanozymes for Rapid and Durable Colorimetric Detection of H2O2

Lijun Li; Xin Liu; Ruonan Zhu; Bo Wang; Jun Yang; Feng Xu; Shri Ramaswamy; Xueming Zhang

doi:10.1021/acssuschemeng.1c03357

Fe³⁺-Doped Aminated Lignin as Peroxidase-Mimicking Nanozymes for Rapid and Durable Colorimetric Detection of H₂O₂

Lijun Li, Xin Liu, Ruonan Zhu, Bo Wang, Jun Yang, Feng Xu, Shri Ramaswamy, Xueming Zhang

Bioproducts and Biosystems Engineering

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

Nanozymes have developed rapidly as substitutes for natural enzymes. However, the toxic synthesis and the use of expensive materials seriously restrict their large-scale applications. To solve these issues, Fe³⁺-doped aminated lignin (Fe-AL) peroxidase-mimicking nanozymes were innovatively synthesized. The active center FeNxwas introduced to alkali lignin by amination via Mannich or epoxidation methods before Fe³⁺-doping. The Fe-AL nanozymes could achieve accurate colorimetric detection of H₂O₂in 10-100 m and could be reused over 30 times with only a negligible decrease in catalytic activity. Besides, the color-developing systems could even maintain the blue color over 72 h, which showed great promise in designing cheap and portable H₂O₂sensors. This work not only can promote the development of lignin-based nanomaterials but also provide a new way for the synthesis of nanozymes from natural macromolecules.

Original language	English (US)
Pages (from-to)	12833-12843
Number of pages	11
Journal	ACS Sustainable Chemistry and Engineering
Volume	9
Issue number	38
DOIs	https://doi.org/10.1021/acssuschemeng.1c03357
State	Published - Sep 27 2021

Bibliographical note

Funding Information:
We are grateful for the financial support by the “World-Class Discipline Construction and Characteristic Development Guidance Funds for Beijing Forestry University” (2019XKJS0330) and the Natural Science Foundation of China (No. 31470606).

Publisher Copyright:
© 2021 American Chemical Society

Keywords

alkali lignin
ferric-ion-doping
nanozymes
peroxidase mimics

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Cite this

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abstract = "Nanozymes have developed rapidly as substitutes for natural enzymes. However, the toxic synthesis and the use of expensive materials seriously restrict their large-scale applications. To solve these issues, Fe3+-doped aminated lignin (Fe-AL) peroxidase-mimicking nanozymes were innovatively synthesized. The active center FeNxwas introduced to alkali lignin by amination via Mannich or epoxidation methods before Fe3+-doping. The Fe-AL nanozymes could achieve accurate colorimetric detection of H2O2in 10-100 m and could be reused over 30 times with only a negligible decrease in catalytic activity. Besides, the color-developing systems could even maintain the blue color over 72 h, which showed great promise in designing cheap and portable H2O2sensors. This work not only can promote the development of lignin-based nanomaterials but also provide a new way for the synthesis of nanozymes from natural macromolecules.",

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AU - Xu, Feng

AU - Ramaswamy, Shri

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