First World Consensus Conference on pancreas transplantation: Part II – recommendations

Ugo Boggi; Fabio Vistoli; Axel Andres; Helmut P. Arbogast; Lionel Badet; Walter Baronti; Stephen T. Bartlett; Enrico Benedetti; Julien Branchereau; George W. Burke; Fanny Buron; Rossana Caldara; Massimo Cardillo; Daniel Casanova; Federica Cipriani; Matthew Cooper; Adamasco Cupisti; Josè Davide; Cinthia Drachenberg; Eelco J.P. de Koning; Giuseppe Maria Ettorre; Laureano Fernandez Cruz; Jonathan A. Fridell; Peter J. Friend; Lucrezia Furian; Osama A. Gaber; Angelika C. Gruessner; Rainer W.G. Gruessner; Jenny E. Gunton; Duck Jong Han; Sara Iacopi; Emanuele Federico Kauffmann; Dixon Kaufman; Takashi Kenmochi; Hussein A. Khambalia; Quirino Lai; Robert M. Langer; Paola Maffi; Lorella Marselli; Francesco Menichetti; Mario Miccoli; Shruti Mittal; Emmanuel Morelon; Niccolò Napoli; Flavia Neri; Jose Oberholzer; Jon S. Odorico; Robert Öllinger; Gabriel Oniscu; Giuseppe Orlando; Monica Ortenzi; Marcelo Perosa; Vittorio Grazio Perrone; Henry Pleass; Robert R. Redfield; Claudio Ricci; Paolo Rigotti; R. Paul Robertson; Lainie F. Ross; Massimo Rossi; Frantisek Saudek; Joseph R. Scalea; Peter Schenker; Antonio Secchi; Carlo Socci; Donzilia Sousa Silva; Jean Paul Squifflet; Peter G. Stock; Robert J. Stratta; Chiara Terrenzio; Pablo Uva; Christopher J.E. Watson; Steven A. White; Piero Marchetti; Raja Kandaswamy; Thierry Berney

doi:10.1111/ajt.16750

First World Consensus Conference on pancreas transplantation: Part II – recommendations

Ugo Boggi, Fabio Vistoli, Axel Andres, Helmut P. Arbogast, Lionel Badet, Walter Baronti, Stephen T. Bartlett, Enrico Benedetti, Julien Branchereau, George W. Burke, Fanny Buron, Rossana Caldara, Massimo Cardillo, Daniel Casanova, Federica Cipriani, Matthew Cooper, Adamasco Cupisti, Josè Davide, Cinthia Drachenberg, Eelco J.P. de KoningGiuseppe Maria Ettorre, Laureano Fernandez Cruz, Jonathan A. Fridell, Peter J. Friend, Lucrezia Furian, Osama A. Gaber, Angelika C. Gruessner, Rainer W.G. Gruessner, Jenny E. Gunton, Duck Jong Han, Sara Iacopi, Emanuele Federico Kauffmann, Dixon Kaufman, Takashi Kenmochi, Hussein A. Khambalia, Quirino Lai, Robert M. Langer, Paola Maffi, Lorella Marselli, Francesco Menichetti, Mario Miccoli, Shruti Mittal, Emmanuel Morelon, Niccolò Napoli, Flavia Neri, Jose Oberholzer, Jon S. Odorico, Robert Öllinger, Gabriel Oniscu, Giuseppe Orlando, Monica Ortenzi, Marcelo Perosa, Vittorio Grazio Perrone, Henry Pleass, Robert R. Redfield, Claudio Ricci, Paolo Rigotti, R. Paul Robertson, Lainie F. Ross, Massimo Rossi, Frantisek Saudek, Joseph R. Scalea, Peter Schenker, Antonio Secchi, Carlo Socci, Donzilia Sousa Silva, Jean Paul Squifflet, Peter G. Stock, Robert J. Stratta, Chiara Terrenzio, Pablo Uva, Christopher J.E. Watson, Steven A. White, Piero Marchetti, Raja Kandaswamy, Thierry Berney

Surgery

Research output: Contribution to journal › Article › peer-review

37 Scopus citations

Abstract

The First World Consensus Conference on Pancreas Transplantation provided 49 jury deliberations regarding the impact of pancreas transplantation on the treatment of diabetic patients, and 110 experts’ recommendations for the practice of pancreas transplantation. The main message from this consensus conference is that both simultaneous pancreas-kidney transplantation (SPK) and pancreas transplantation alone can improve long-term patient survival, and all types of pancreas transplantation dramatically improve the quality of life of recipients. Pancreas transplantation may also improve the course of chronic complications of diabetes, depending on their severity. Therefore, the advantages of pancreas transplantation appear to clearly surpass potential disadvantages. Pancreas after kidney transplantation increases the risk of mortality only in the early period after transplantation, but is associated with improved life expectancy thereafter. Additionally, preemptive SPK, when compared to SPK performed in patients undergoing dialysis, appears to be associated with improved outcomes. Time on dialysis has negative prognostic implications in SPK recipients. Increased long-term survival, improvement in the course of diabetic complications, and amelioration of quality of life justify preferential allocation of kidney grafts to SPK recipients. Audience discussions and live voting are available online at the following URL address: http://mediaeventi.unipi.it/category/1st-world-consensus-conference-of-pancreas-transplantation/246.

Original language	English (US)
Pages (from-to)	17-59
Number of pages	43
Journal	American Journal of Transplantation
Volume	21
Issue number	S3
DOIs	https://doi.org/10.1111/ajt.16750
State	Published - Sep 2021

Bibliographical note

Publisher Copyright:
© 2021 The Authors. American Journal of Transplantation published by Wiley Periodicals LLC on behalf of The American Society of Transplantation and the American Society of Transplant Surgeons

Keywords

clinical research/practice
diabetes
pancreas/simultaneous pancreas-kidney transplantation
survey

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1111/ajt.16750

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Boggi, U., Vistoli, F., Andres, A., Arbogast, H. P., Badet, L., Baronti, W., Bartlett, S. T., Benedetti, E., Branchereau, J., Burke, G. W., Buron, F., Caldara, R., Cardillo, M., Casanova, D., Cipriani, F., Cooper, M., Cupisti, A., Davide, J., Drachenberg, C., ... Berney, T. (2021). First World Consensus Conference on pancreas transplantation: Part II – recommendations. American Journal of Transplantation, 21(S3), 17-59. https://doi.org/10.1111/ajt.16750

Boggi, U, Vistoli, F, Andres, A, Arbogast, HP, Badet, L, Baronti, W, Bartlett, ST, Benedetti, E, Branchereau, J, Burke, GW, Buron, F, Caldara, R, Cardillo, M, Casanova, D, Cipriani, F, Cooper, M, Cupisti, A, Davide, J, Drachenberg, C, de Koning, EJP, Ettorre, GM, Fernandez Cruz, L, Fridell, JA, Friend, PJ, Furian, L, Gaber, OA, Gruessner, AC, Gruessner, RWG, Gunton, JE, Han, DJ, Iacopi, S, Kauffmann, EF, Kaufman, D, Kenmochi, T, Khambalia, HA, Lai, Q, Langer, RM, Maffi, P, Marselli, L, Menichetti, F, Miccoli, M, Mittal, S, Morelon, E, Napoli, N, Neri, F, Oberholzer, J, Odorico, JS, Öllinger, R, Oniscu, G, Orlando, G, Ortenzi, M, Perosa, M, Perrone, VG, Pleass, H, Redfield, RR, Ricci, C, Rigotti, P, Paul Robertson, R, Ross, LF, Rossi, M, Saudek, F, Scalea, JR, Schenker, P, Secchi, A, Socci, C, Sousa Silva, D, Squifflet, JP, Stock, PG, Stratta, RJ, Terrenzio, C, Uva, P, Watson, CJE, White, SA, Marchetti, P, Kandaswamy, R & Berney, T 2021, 'First World Consensus Conference on pancreas transplantation: Part II – recommendations', American Journal of Transplantation, vol. 21, no. S3, pp. 17-59. https://doi.org/10.1111/ajt.16750

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title = "First World Consensus Conference on pancreas transplantation: Part II – recommendations",

abstract = "The First World Consensus Conference on Pancreas Transplantation provided 49 jury deliberations regarding the impact of pancreas transplantation on the treatment of diabetic patients, and 110 experts{\textquoteright} recommendations for the practice of pancreas transplantation. The main message from this consensus conference is that both simultaneous pancreas-kidney transplantation (SPK) and pancreas transplantation alone can improve long-term patient survival, and all types of pancreas transplantation dramatically improve the quality of life of recipients. Pancreas transplantation may also improve the course of chronic complications of diabetes, depending on their severity. Therefore, the advantages of pancreas transplantation appear to clearly surpass potential disadvantages. Pancreas after kidney transplantation increases the risk of mortality only in the early period after transplantation, but is associated with improved life expectancy thereafter. Additionally, preemptive SPK, when compared to SPK performed in patients undergoing dialysis, appears to be associated with improved outcomes. Time on dialysis has negative prognostic implications in SPK recipients. Increased long-term survival, improvement in the course of diabetic complications, and amelioration of quality of life justify preferential allocation of kidney grafts to SPK recipients. Audience discussions and live voting are available online at the following URL address: http://mediaeventi.unipi.it/category/1st-world-consensus-conference-of-pancreas-transplantation/246.",

keywords = "clinical research/practice, diabetes, pancreas/simultaneous pancreas-kidney transplantation, survey",

author = "Ugo Boggi and Fabio Vistoli and Axel Andres and Arbogast, {Helmut P.} and Lionel Badet and Walter Baronti and Bartlett, {Stephen T.} and Enrico Benedetti and Julien Branchereau and Burke, {George W.} and Fanny Buron and Rossana Caldara and Massimo Cardillo and Daniel Casanova and Federica Cipriani and Matthew Cooper and Adamasco Cupisti and Jos{\`e} Davide and Cinthia Drachenberg and {de Koning}, {Eelco J.P.} and Ettorre, {Giuseppe Maria} and {Fernandez Cruz}, Laureano and Fridell, {Jonathan A.} and Friend, {Peter J.} and Lucrezia Furian and Gaber, {Osama A.} and Gruessner, {Angelika C.} and Gruessner, {Rainer W.G.} and Gunton, {Jenny E.} and Han, {Duck Jong} and Sara Iacopi and Kauffmann, {Emanuele Federico} and Dixon Kaufman and Takashi Kenmochi and Khambalia, {Hussein A.} and Quirino Lai and Langer, {Robert M.} and Paola Maffi and Lorella Marselli and Francesco Menichetti and Mario Miccoli and Shruti Mittal and Emmanuel Morelon and Niccol{\`o} Napoli and Flavia Neri and Jose Oberholzer and Odorico, {Jon S.} and Robert {\"O}llinger and Gabriel Oniscu and Giuseppe Orlando and Monica Ortenzi and Marcelo Perosa and Perrone, {Vittorio Grazio} and Henry Pleass and Redfield, {Robert R.} and Claudio Ricci and Paolo Rigotti and {Paul Robertson}, R. and Ross, {Lainie F.} and Massimo Rossi and Frantisek Saudek and Scalea, {Joseph R.} and Peter Schenker and Antonio Secchi and Carlo Socci and {Sousa Silva}, Donzilia and Squifflet, {Jean Paul} and Stock, {Peter G.} and Stratta, {Robert J.} and Chiara Terrenzio and Pablo Uva and Watson, {Christopher J.E.} and White, {Steven A.} and Piero Marchetti and Raja Kandaswamy and Thierry Berney",

note = "Publisher Copyright: {\textcopyright} 2021 The Authors. American Journal of Transplantation published by Wiley Periodicals LLC on behalf of The American Society of Transplantation and the American Society of Transplant Surgeons",

year = "2021",

month = sep,

doi = "10.1111/ajt.16750",

language = "English (US)",

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T1 - First World Consensus Conference on pancreas transplantation

T2 - Part II – recommendations

AU - Boggi, Ugo

AU - Vistoli, Fabio

AU - Andres, Axel

AU - Arbogast, Helmut P.

AU - Badet, Lionel

AU - Baronti, Walter

AU - Bartlett, Stephen T.

AU - Benedetti, Enrico

AU - Branchereau, Julien

AU - Burke, George W.

AU - Buron, Fanny

AU - Caldara, Rossana

AU - Cardillo, Massimo

AU - Casanova, Daniel

AU - Cipriani, Federica

AU - Cooper, Matthew

AU - Cupisti, Adamasco

AU - Davide, Josè

AU - Drachenberg, Cinthia

AU - de Koning, Eelco J.P.

AU - Ettorre, Giuseppe Maria

AU - Fernandez Cruz, Laureano

AU - Fridell, Jonathan A.

AU - Friend, Peter J.

AU - Furian, Lucrezia

AU - Gaber, Osama A.

AU - Gruessner, Angelika C.

AU - Gruessner, Rainer W.G.

AU - Gunton, Jenny E.

AU - Han, Duck Jong

AU - Iacopi, Sara

AU - Kauffmann, Emanuele Federico

AU - Kaufman, Dixon

AU - Kenmochi, Takashi

AU - Khambalia, Hussein A.

AU - Lai, Quirino

AU - Langer, Robert M.

AU - Maffi, Paola

AU - Marselli, Lorella

AU - Menichetti, Francesco

AU - Miccoli, Mario

AU - Mittal, Shruti

AU - Morelon, Emmanuel

AU - Napoli, Niccolò

AU - Neri, Flavia

AU - Oberholzer, Jose

AU - Odorico, Jon S.

AU - Öllinger, Robert

AU - Oniscu, Gabriel

AU - Orlando, Giuseppe

AU - Ortenzi, Monica

AU - Perosa, Marcelo

AU - Perrone, Vittorio Grazio

AU - Pleass, Henry

AU - Redfield, Robert R.

AU - Ricci, Claudio

AU - Rigotti, Paolo

AU - Paul Robertson, R.

AU - Ross, Lainie F.

AU - Rossi, Massimo

AU - Saudek, Frantisek

AU - Scalea, Joseph R.

AU - Schenker, Peter

AU - Secchi, Antonio

AU - Socci, Carlo

AU - Sousa Silva, Donzilia

AU - Squifflet, Jean Paul

AU - Stock, Peter G.

AU - Stratta, Robert J.

AU - Terrenzio, Chiara

AU - Uva, Pablo

AU - Watson, Christopher J.E.

AU - White, Steven A.

AU - Marchetti, Piero

AU - Kandaswamy, Raja

AU - Berney, Thierry

N1 - Publisher Copyright: © 2021 The Authors. American Journal of Transplantation published by Wiley Periodicals LLC on behalf of The American Society of Transplantation and the American Society of Transplant Surgeons

PY - 2021/9

Y1 - 2021/9

N2 - The First World Consensus Conference on Pancreas Transplantation provided 49 jury deliberations regarding the impact of pancreas transplantation on the treatment of diabetic patients, and 110 experts’ recommendations for the practice of pancreas transplantation. The main message from this consensus conference is that both simultaneous pancreas-kidney transplantation (SPK) and pancreas transplantation alone can improve long-term patient survival, and all types of pancreas transplantation dramatically improve the quality of life of recipients. Pancreas transplantation may also improve the course of chronic complications of diabetes, depending on their severity. Therefore, the advantages of pancreas transplantation appear to clearly surpass potential disadvantages. Pancreas after kidney transplantation increases the risk of mortality only in the early period after transplantation, but is associated with improved life expectancy thereafter. Additionally, preemptive SPK, when compared to SPK performed in patients undergoing dialysis, appears to be associated with improved outcomes. Time on dialysis has negative prognostic implications in SPK recipients. Increased long-term survival, improvement in the course of diabetic complications, and amelioration of quality of life justify preferential allocation of kidney grafts to SPK recipients. Audience discussions and live voting are available online at the following URL address: http://mediaeventi.unipi.it/category/1st-world-consensus-conference-of-pancreas-transplantation/246.

AB - The First World Consensus Conference on Pancreas Transplantation provided 49 jury deliberations regarding the impact of pancreas transplantation on the treatment of diabetic patients, and 110 experts’ recommendations for the practice of pancreas transplantation. The main message from this consensus conference is that both simultaneous pancreas-kidney transplantation (SPK) and pancreas transplantation alone can improve long-term patient survival, and all types of pancreas transplantation dramatically improve the quality of life of recipients. Pancreas transplantation may also improve the course of chronic complications of diabetes, depending on their severity. Therefore, the advantages of pancreas transplantation appear to clearly surpass potential disadvantages. Pancreas after kidney transplantation increases the risk of mortality only in the early period after transplantation, but is associated with improved life expectancy thereafter. Additionally, preemptive SPK, when compared to SPK performed in patients undergoing dialysis, appears to be associated with improved outcomes. Time on dialysis has negative prognostic implications in SPK recipients. Increased long-term survival, improvement in the course of diabetic complications, and amelioration of quality of life justify preferential allocation of kidney grafts to SPK recipients. Audience discussions and live voting are available online at the following URL address: http://mediaeventi.unipi.it/category/1st-world-consensus-conference-of-pancreas-transplantation/246.

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KW - diabetes

KW - pancreas/simultaneous pancreas-kidney transplantation

KW - survey

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DO - 10.1111/ajt.16750

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SN - 1600-6135

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JO - American Journal of Transplantation

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IS - S3

ER -

First World Consensus Conference on pancreas transplantation: Part II – recommendations

Abstract

Bibliographical note

Keywords

UN SDGs

Access

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