Gallstones in chronic spinal cord injury: Is impaired gallbladder emptying a risk factor?

Scott R. Ketover; Howard J. Ansel; Gary Goldish; Brenda Roche; Roger L. Gebhard

doi:10.1016/S0003-9993(96)90136-7

Gallstones in chronic spinal cord injury: Is impaired gallbladder emptying a risk factor?

Scott R. Ketover, Howard J. Ansel, Gary Goldish, Brenda Roche, Roger L. Gebhard

Radiology

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

Objectives: To confirm that spinal cord injured persons are susceptible to gallstones and to evaluate the role of gallbladder stasis as a risk factor. Study Design: Twenty-nine subjects with chronic spinal cord injury underwent fasting ultrasonography to determine the incidence of gallstones and to quantitate gallbladder emptying response to a 20g fat liquid meal. Gallbladder emptying fraction was compared to that of healthy subjects studied concurrently. Results: Gallstones or sludge were found in 6 spinal cord injured men, a minimal prevalence of 21%. Four additional subjects had prior cholecystectomy for stones, giving a potential maximal prevalence of 30%. Four of the 6 subjects had gallstone risk factors of diabetes, obesity, and/or family history. Gallbladder stasis was not apparent in chronic spinal cord injured subjects. Only 5 subjects had poor gallbladder emptying, and 4 of them had diabetes and/or obesity. Conclusions: The study confirms an increased prevalence of gallstones after spinal cord injury. However, gallbladder stasis did not appear to be etiologic, and most gallstones were associated with conventional risk factors. The results do not support a general policy of gallstone screening or prophylactic therapy after spinal cord injury.

Original language	English (US)
Pages (from-to)	1136-1138
Number of pages	3
Journal	Archives of Physical Medicine and Rehabilitation
Volume	77
Issue number	11
DOIs	https://doi.org/10.1016/S0003-9993(96)90136-7
State	Published - Nov 1996

Bibliographical note

Funding Information:
From the Departments of Medicine (Drs. Ketover and Gebhard), Radiology (Dr. Ansel), and Physical Medicine and Rehabilitation (Dr. Goldish, Ms. Roche). Department of Veterans Affairs Medical Center and University of Minnesota, Minneapolis. Submitted for publication January 22, 1996. Accepted March 25, 1996. Supported by the Department of Veterans Affairs Research Service. No commercial party having a direct financial interest in the results of the research supporting this article has or will confer a benefit upon the authors or upon any organization with which the authors are associated. Reprint requests to Roger L. Gebhard, MD, Gastroenterology Section (I I ID), VA Medical Center, One Veterans Drive. Minneapolis, MN 55417. This is a US government work. There are no restrictions on its use. 0003.9993/96/77 I I -3857$0.00/O

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title = "Gallstones in chronic spinal cord injury: Is impaired gallbladder emptying a risk factor?",

abstract = "Objectives: To confirm that spinal cord injured persons are susceptible to gallstones and to evaluate the role of gallbladder stasis as a risk factor. Study Design: Twenty-nine subjects with chronic spinal cord injury underwent fasting ultrasonography to determine the incidence of gallstones and to quantitate gallbladder emptying response to a 20g fat liquid meal. Gallbladder emptying fraction was compared to that of healthy subjects studied concurrently. Results: Gallstones or sludge were found in 6 spinal cord injured men, a minimal prevalence of 21%. Four additional subjects had prior cholecystectomy for stones, giving a potential maximal prevalence of 30%. Four of the 6 subjects had gallstone risk factors of diabetes, obesity, and/or family history. Gallbladder stasis was not apparent in chronic spinal cord injured subjects. Only 5 subjects had poor gallbladder emptying, and 4 of them had diabetes and/or obesity. Conclusions: The study confirms an increased prevalence of gallstones after spinal cord injury. However, gallbladder stasis did not appear to be etiologic, and most gallstones were associated with conventional risk factors. The results do not support a general policy of gallstone screening or prophylactic therapy after spinal cord injury.",

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N2 - Objectives: To confirm that spinal cord injured persons are susceptible to gallstones and to evaluate the role of gallbladder stasis as a risk factor. Study Design: Twenty-nine subjects with chronic spinal cord injury underwent fasting ultrasonography to determine the incidence of gallstones and to quantitate gallbladder emptying response to a 20g fat liquid meal. Gallbladder emptying fraction was compared to that of healthy subjects studied concurrently. Results: Gallstones or sludge were found in 6 spinal cord injured men, a minimal prevalence of 21%. Four additional subjects had prior cholecystectomy for stones, giving a potential maximal prevalence of 30%. Four of the 6 subjects had gallstone risk factors of diabetes, obesity, and/or family history. Gallbladder stasis was not apparent in chronic spinal cord injured subjects. Only 5 subjects had poor gallbladder emptying, and 4 of them had diabetes and/or obesity. Conclusions: The study confirms an increased prevalence of gallstones after spinal cord injury. However, gallbladder stasis did not appear to be etiologic, and most gallstones were associated with conventional risk factors. The results do not support a general policy of gallstone screening or prophylactic therapy after spinal cord injury.

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Gallstones in chronic spinal cord injury: Is impaired gallbladder emptying a risk factor?

Abstract

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