Genetic basis for the origin of cardiac arrhythmias: Implications for therapy

Mackenzi Mbai, Sridharan Rajamani, Brian P. Delisle, Blake D. Anson, Corey Anderson, Jonathan C. Makielski, Craig T. January

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

The recognition of the role that genetic abnormalities play in the generation of cardiac arrhythmias and sudden cardiac death has evolved enormously over the past decade. One result is new insight into underlying physiologic and pathophysiologic mechanisms. New therapies based on this evolving insight are being developed. This review summarizes recent discoveries with a focus on the genetic basis of cardiac arrhythmias and their implications for new therapies.

Original languageEnglish (US)
Pages (from-to)411-417
Number of pages7
JournalCurrent Cardiology Reports
Volume4
Issue number5
DOIs
StatePublished - 2002

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