Genome sequence of human cytomegalovirus Ig-KG-H2, a variant of strain KG propagated in the presence of neutralizing antibodies

Ahmed Al Qaffas; Salvatore Camiolo; Jenna Nichols; Andrew J. Davison; Amine Ourahmane; Xiaohong Cui; Mark R. Schleiss; Laura Hertel; Dirk P. Dittmer; Michael A. McVoy

doi:10.1128/MRA.00063-20

Genome sequence of human cytomegalovirus Ig-KG-H2, a variant of strain KG propagated in the presence of neutralizing antibodies

Ahmed Al Qaffas, Salvatore Camiolo, Jenna Nichols, Andrew J. Davison, Amine Ourahmane, Xiaohong Cui, Mark R. Schleiss, Laura Hertel, Dirk P. Dittmer, Michael A. McVoy

Pediatrics - Infectious Disease

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2 Scopus citations

Abstract

Human cytomegalovirus shed in infant urine was isolated and serially passaged in fibroblasts in the presence or absence of neutralizing antibodies. Comparison of the genome sequences of representative viruses Ig-KG-H2 (passed with antibody) and ϕ-KG-B5 (passed without antibody) revealed the presence of several mutations in each virus.

Original language	English (US)
Article number	e00063-20
Journal	Microbiology Resource Announcements
Volume	9
Issue number	17
DOIs	https://doi.org/10.1128/MRA.00063-20
State	Published - Apr 23 2020

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Copyright © 2020 Al Qaffas et al.

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Al Qaffas, A., Camiolo, S., Nichols, J., Davison, A. J., Ourahmane, A., Cui, X., Schleiss, M. R., Hertel, L., Dittmer, D. P., & McVoy, M. A. (2020). Genome sequence of human cytomegalovirus Ig-KG-H2, a variant of strain KG propagated in the presence of neutralizing antibodies. Microbiology Resource Announcements, 9(17), Article e00063-20. https://doi.org/10.1128/MRA.00063-20

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AU - Davison, Andrew J.

AU - Ourahmane, Amine

AU - Cui, Xiaohong

AU - Schleiss, Mark R.

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AU - Dittmer, Dirk P.

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Genome sequence of human cytomegalovirus Ig-KG-H2, a variant of strain KG propagated in the presence of neutralizing antibodies

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