Harnessing endogenous intra- and extra-cardiac stem cells for cardiac regeneration - Hope or hype?

Sunny Sun Kin Chan; Ying Zhang Shueh; Yen Wen Liu; Patrick C H Hsieh

doi:10.1016/j.ddstr.2009.06.004

Harnessing endogenous intra- and extra-cardiac stem cells for cardiac regeneration - Hope or hype?

Sunny Sun Kin Chan, Ying Zhang Shueh, Yen Wen Liu, Patrick C H Hsieh

Pediatrics - Blood/Marrow Transplant

Research output: Contribution to journal › Review article › peer-review

6 Scopus citations

Abstract

Recent findings revealed endogenous cardiomyocyte replenishment upon myocardial injuries in mice and continuous cardiomyocyte renewal throughout the human life. These important findings not only confirmed the cardiac regenerative potentials of the adult myocardium, but also hinted a novel strategy for cardiac repair by renewing cardiomyocytes. In this review, we discuss target cardiogenic stem cell populations and approaches to unleash their cardiac regeneration potentials.

Original language	English (US)
Pages (from-to)	127-133
Number of pages	7
Journal	Drug Discovery Today: Therapeutic Strategies
Volume	6
Issue number	4
DOIs	https://doi.org/10.1016/j.ddstr.2009.06.004
State	Published - 2009

Bibliographical note

Funding Information:
This work was supported by the National Science Council (grant numbers NSC 97-IR-082, NSC 96-2314-B-006-021 and NSC 97-3111-B-006-005), the National Health Research Institutes (grant number NHRI EX97-22SI) and the NCKU Integrated Landmark Project (grant number 97-I006).

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@article{78b57eb4b1db484682fbbfd60eb0696d,

title = "Harnessing endogenous intra- and extra-cardiac stem cells for cardiac regeneration - Hope or hype?",

abstract = "Recent findings revealed endogenous cardiomyocyte replenishment upon myocardial injuries in mice and continuous cardiomyocyte renewal throughout the human life. These important findings not only confirmed the cardiac regenerative potentials of the adult myocardium, but also hinted a novel strategy for cardiac repair by renewing cardiomyocytes. In this review, we discuss target cardiogenic stem cell populations and approaches to unleash their cardiac regeneration potentials.",

author = "Chan, {Sunny Sun Kin} and Shueh, {Ying Zhang} and Liu, {Yen Wen} and Hsieh, {Patrick C H}",

note = "Funding Information: This work was supported by the National Science Council (grant numbers NSC 97-IR-082, NSC 96-2314-B-006-021 and NSC 97-3111-B-006-005), the National Health Research Institutes (grant number NHRI EX97-22SI) and the NCKU Integrated Landmark Project (grant number 97-I006).",

year = "2009",

doi = "10.1016/j.ddstr.2009.06.004",

language = "English (US)",

volume = "6",

pages = "127--133",

journal = "Drug Discovery Today: Therapeutic Strategies",

issn = "1740-6773",