Abstract
This study compares the effectiveness of hepatic arterial infusion of mitomycin C with that of 5 fluorouracil in the management of carcinoma of the colon metastatic to the liver. A higher tumor response rate was obtained with 5 FU (10 of 12 patients) than with mitomycin C (6 of 13 patients). The patients treated with mitomycin C had a median survival time of 9.5 mth compared to 12 mth for those receiving 5 FU, but this survival is not much different from that of the untreated historical controls. Femoral artery thrombosis requiring surgical thrombectomy developed in 5 of the 30 catheterized patients.
Original language | English (US) |
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Pages (from-to) | 401-404 |
Number of pages | 4 |
Journal | CANCER CHEMOTHER.REP. |
Volume | 59 |
Issue number | 2 |
State | Published - Dec 1 1975 |