Abstract
(Chemical Equation Presented) Homogeneous carboamination, carboalkoxylation and carbolactonization of terminal alkenes are realized via oxidative gold catalysis, providing expedient access to various substituted Nor O-heterocycles. Deuterium-labeling studies established the anti nature of the alkene functionalization and the indispensible role of Au(I)/Au(III) catalysis. This study constitutes the first example of catalytically converting C(sp 3)-Au bonds into C(sp3)-C(sp2) bonds in a crosscoupling manner and opens new opportunities to study gold alkene catalysis where alkylgold intermediates can be readily functionalized intermolecularly.
Original language | English (US) |
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Pages (from-to) | 1474-1475 |
Number of pages | 2 |
Journal | Journal of the American Chemical Society |
Volume | 132 |
Issue number | 5 |
DOIs | |
State | Published - Feb 10 2010 |
Externally published | Yes |