Host factors and consequence of chemotherapy in pediatric cancer patients

L'Aurelle A. Johnson; Julie A. Ross

doi:10.1002/pbc.21630

Host factors and consequence of chemotherapy in pediatric cancer patients

L'Aurelle A. Johnson, Julie A. Ross

Research output: Contribution to journal › Review article › peer-review

3 Scopus citations

Abstract

The 5-year survival rates for childhood ALL are approaching 80%, but therapy-related toxicities are common. One of the challenges in this population is determining the most efficacious therapeutic regimens for these individuals. Factors such as drug metabolism, genetics, and concomitant disease affect drug efficacy and may be important in determining therapeutic outcomes in these patients. This review will focus on these factors in the treatment of childhood ALL.

Original language	English (US)
Pages (from-to)	320-326
Number of pages	7
Journal	Pediatric Blood and Cancer
Volume	51
Issue number	3
DOIs	https://doi.org/10.1002/pbc.21630
State	Published - Sep 2008

Keywords

ALL
Pediatric oncology
Pharmacology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access

10.1002/pbc.21630

OpenUrl availability

Full text

Cite this

@article{e40cbcc748114f8ab0cbe8458cf7bf32,

title = "Host factors and consequence of chemotherapy in pediatric cancer patients",

abstract = "The 5-year survival rates for childhood ALL are approaching 80%, but therapy-related toxicities are common. One of the challenges in this population is determining the most efficacious therapeutic regimens for these individuals. Factors such as drug metabolism, genetics, and concomitant disease affect drug efficacy and may be important in determining therapeutic outcomes in these patients. This review will focus on these factors in the treatment of childhood ALL.",

keywords = "ALL, Pediatric oncology, Pharmacology",

author = "Johnson, {L'Aurelle A.} and Ross, {Julie A.}",

year = "2008",

month = sep,

doi = "10.1002/pbc.21630",

language = "English (US)",

volume = "51",

pages = "320--326",

journal = "Pediatric Blood and Cancer",

issn = "1545-5009",

publisher = "Wiley-Liss Inc.",

number = "3",

}

TY - JOUR

T1 - Host factors and consequence of chemotherapy in pediatric cancer patients

AU - Johnson, L'Aurelle A.

AU - Ross, Julie A.

PY - 2008/9

Y1 - 2008/9

N2 - The 5-year survival rates for childhood ALL are approaching 80%, but therapy-related toxicities are common. One of the challenges in this population is determining the most efficacious therapeutic regimens for these individuals. Factors such as drug metabolism, genetics, and concomitant disease affect drug efficacy and may be important in determining therapeutic outcomes in these patients. This review will focus on these factors in the treatment of childhood ALL.

AB - The 5-year survival rates for childhood ALL are approaching 80%, but therapy-related toxicities are common. One of the challenges in this population is determining the most efficacious therapeutic regimens for these individuals. Factors such as drug metabolism, genetics, and concomitant disease affect drug efficacy and may be important in determining therapeutic outcomes in these patients. This review will focus on these factors in the treatment of childhood ALL.

KW - ALL

KW - Pediatric oncology

KW - Pharmacology

UR - http://www.scopus.com/inward/record.url?scp=48249148305&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=48249148305&partnerID=8YFLogxK

U2 - 10.1002/pbc.21630

DO - 10.1002/pbc.21630

M3 - Review article

C2 - 18506759

AN - SCOPUS:48249148305

SN - 1545-5009

VL - 51

SP - 320

EP - 326

JO - Pediatric Blood and Cancer

JF - Pediatric Blood and Cancer

IS - 3

ER -

Host factors and consequence of chemotherapy in pediatric cancer patients

Abstract

Keywords

UN SDGs

Access

OpenUrl availability

Other files and links

Fingerprint

Cite this