Hypoxic culture and insulin yield improvements to fibrin-based engineered tissue

Engineering & Materials Science

• Insulin 100%
• Collagen 98%
• Tissue 63%
• Oxygen 13%
• Phosphorylation 13%
• Tensile strength 13%
• Fibroblasts 12%
• Strength of materials 8%
• Molecules 8%
• Elastic moduli 6%
• Stiffness 5%
• Mechanical properties 5%

Medicine & Life Sciences

• Fibrin 76%
• Collagen 56%
• Insulin 50%
• Tensile Strength 19%
• Oxygen 11%
• Prolyl Hydroxylases 11%
• Post Translational Protein Processing 8%
• Hypoxia 6%
• Fibroblasts 6%
• Phosphorylation 5%
• Western Blotting 5%
• Skin 4%

Chemical Compounds

• Insulin Derivative 76%
• Collagen 70%
• Reaction Yield 30%
• Tension 15%
• Tensile Strength 13%
• Dioxygen 8%
• Strength 5%
• Modification 4%
• Molecule 2%