Immune Cell Metabolism and Function

Ajay Dixit; Mahendra Singh

doi:10.1007/978-981-16-6226-3_1

Immune Cell Metabolism and Function

Ajay Dixit, Mahendra Singh

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Immune cells are highly dynamic by nature and rely on metabolism to adapt to different conditions. Many recent studies have shown the importance of immune cells and their metabolism in the pathogenesis of many diseases. Cellular metabolism acts as a guiding force to regulate immune cell activation, differentiation, and cellular behavior, thus regulating the extent of the immune response. Here in this chapter, we have discussed different metabolic signatures and pathways that control the activation status of immune cells and how the change in the metabolic status affects the immune response, disease pathobiology, and homeostasis especially in cancer.

Original language	English (US)
Title of host publication	Immuno-Oncology Crosstalk and Metabolism
Publisher	Springer Nature
Pages	1-20
Number of pages	20
ISBN (Electronic)	9789811662263
ISBN (Print)	9789811662256
DOIs	https://doi.org/10.1007/978-981-16-6226-3_1
State	Published - Jan 1 2022
Externally published	Yes

Bibliographical note

Publisher Copyright:
© The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2022.

Keywords

Amino acids
Glycolysis
Immune-metabolite
Lipids
Metabolism
Redox

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access

10.1007/978-981-16-6226-3_1

OpenUrl availability

Full text

Cite this

@inbook{7926ea60a49b4e139f252a9a5231550e,

title = "Immune Cell Metabolism and Function",

abstract = "Immune cells are highly dynamic by nature and rely on metabolism to adapt to different conditions. Many recent studies have shown the importance of immune cells and their metabolism in the pathogenesis of many diseases. Cellular metabolism acts as a guiding force to regulate immune cell activation, differentiation, and cellular behavior, thus regulating the extent of the immune response. Here in this chapter, we have discussed different metabolic signatures and pathways that control the activation status of immune cells and how the change in the metabolic status affects the immune response, disease pathobiology, and homeostasis especially in cancer.",

keywords = "Amino acids, Glycolysis, Immune-metabolite, Lipids, Metabolism, Redox",

author = "Ajay Dixit and Mahendra Singh",

note = "Publisher Copyright: {\textcopyright} The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2022.",

year = "2022",

month = jan,

day = "1",

doi = "10.1007/978-981-16-6226-3_1",

language = "English (US)",

isbn = "9789811662256",

pages = "1--20",

booktitle = "Immuno-Oncology Crosstalk and Metabolism",

publisher = "Springer Nature",

address = "United States",

}

TY - CHAP

T1 - Immune Cell Metabolism and Function

AU - Dixit, Ajay

AU - Singh, Mahendra

N1 - Publisher Copyright: © The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2022.

PY - 2022/1/1

Y1 - 2022/1/1

N2 - Immune cells are highly dynamic by nature and rely on metabolism to adapt to different conditions. Many recent studies have shown the importance of immune cells and their metabolism in the pathogenesis of many diseases. Cellular metabolism acts as a guiding force to regulate immune cell activation, differentiation, and cellular behavior, thus regulating the extent of the immune response. Here in this chapter, we have discussed different metabolic signatures and pathways that control the activation status of immune cells and how the change in the metabolic status affects the immune response, disease pathobiology, and homeostasis especially in cancer.

AB - Immune cells are highly dynamic by nature and rely on metabolism to adapt to different conditions. Many recent studies have shown the importance of immune cells and their metabolism in the pathogenesis of many diseases. Cellular metabolism acts as a guiding force to regulate immune cell activation, differentiation, and cellular behavior, thus regulating the extent of the immune response. Here in this chapter, we have discussed different metabolic signatures and pathways that control the activation status of immune cells and how the change in the metabolic status affects the immune response, disease pathobiology, and homeostasis especially in cancer.

KW - Amino acids

KW - Glycolysis

KW - Immune-metabolite

KW - Lipids

KW - Metabolism

KW - Redox

UR - http://www.scopus.com/inward/record.url?scp=85160177873&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85160177873&partnerID=8YFLogxK

U2 - 10.1007/978-981-16-6226-3_1

DO - 10.1007/978-981-16-6226-3_1

M3 - Chapter

AN - SCOPUS:85160177873

SN - 9789811662256

SP - 1

EP - 20

BT - Immuno-Oncology Crosstalk and Metabolism

PB - Springer Nature

ER -

Immune Cell Metabolism and Function

Abstract

Bibliographical note

Keywords

UN SDGs

Access

OpenUrl availability

Other files and links

Fingerprint

Cite this