In vitro characterization of movement, heating and visualization of magnetic nanoparticles for biomedical applications

Venkatasubramaniam S. Kalambur, Bumsoo Han, Bruce E. Hammer, Thomas W. Shield, John C. Bischof

Research output: Contribution to journalArticlepeer-review

161 Scopus citations

Abstract

A characterization of the movement and heating of three different types of magnetic nanoparticles in physiological systems in vitro is made in a known external magnetic field and alternating field. Infra-red (IR) imaging and MR imaging are used to visualize the nanoparticles in vitro. It is observes that the time taken by a collection of the nanoparticles to move even a smaller distance in collagen is almost ten times higher as compared to the time taken in glycerol. It is found that the amount of temperature rise increases with the concentration of nanoparticles.

Original languageEnglish (US)
Pages (from-to)1221-1233
Number of pages13
JournalNanotechnology
Volume16
Issue number8
DOIs
StatePublished - Aug 1 2005

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