In vitro virucidal activity of a commercial disinfectant against viruses of domestic animals and poultry

Nader M. Sobhy, Angie Quinonez-Munoz, Hamada A Aboubakr, Christiana R.B. Youssef, Gonzalo Ojeda-Barría, Jonathan Mendoza-Fernández, Sagar M. Goyal

Research output: Contribution to journalArticlepeer-review

Abstract

Outbreaks of viral diseases in animals are a cause of concern for animal welfare and economics of animal production. One way to disrupt the cycle of infection is by combating viruses in the environment and prohibiting them from being transmitted to a new host. Viral contamination of the environment can be reduced using well-tested and efficacious disinfectants. Duplalim is a commercially available disinfectant consisting of 12% glutaraldehyde and 10% quaternary ammonium compounds. We evaluated this disinfectant for its efficacy against several viruses in poultry (n = 3), pigs (n = 5), dogs (n = 2), and cattle (n = 4). In suspension tests, 1:100 dilution of Duplalim was found to inactivate more than 99% of these 14 viruses in 15 min or less. The titers of a majority of these viruses decreased by ≥99.99% in <60 min of contact time. In conclusion, the ingredient combination in Duplalim is very effective in inactivating common viruses of domestic animals and poultry.

Original languageEnglish (US)
Article number1276031
JournalFrontiers in Veterinary Science
Volume10
DOIs
StatePublished - 2023

Bibliographical note

Publisher Copyright:
Copyright © 2024 Sobhy, Quinonez-Munoz, Aboubakr, Youssef, Ojeda-Barría, Mendoza-Fernández and Goyal.

Keywords

  • disinfection
  • Duplalim
  • inactivation
  • suspension test
  • virus

PubMed: MeSH publication types

  • Journal Article

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