TY - JOUR
T1 - In vitro virucidal activity of a commercial disinfectant against viruses of domestic animals and poultry
AU - Sobhy, Nader M.
AU - Quinonez-Munoz, Angie
AU - Aboubakr, Hamada A
AU - Youssef, Christiana R.B.
AU - Ojeda-Barría, Gonzalo
AU - Mendoza-Fernández, Jonathan
AU - Goyal, Sagar M.
N1 - Publisher Copyright:
Copyright © 2024 Sobhy, Quinonez-Munoz, Aboubakr, Youssef, Ojeda-Barría, Mendoza-Fernández and Goyal.
PY - 2023
Y1 - 2023
N2 - Outbreaks of viral diseases in animals are a cause of concern for animal welfare and economics of animal production. One way to disrupt the cycle of infection is by combating viruses in the environment and prohibiting them from being transmitted to a new host. Viral contamination of the environment can be reduced using well-tested and efficacious disinfectants. Duplalim is a commercially available disinfectant consisting of 12% glutaraldehyde and 10% quaternary ammonium compounds. We evaluated this disinfectant for its efficacy against several viruses in poultry (n = 3), pigs (n = 5), dogs (n = 2), and cattle (n = 4). In suspension tests, 1:100 dilution of Duplalim was found to inactivate more than 99% of these 14 viruses in 15 min or less. The titers of a majority of these viruses decreased by ≥99.99% in <60 min of contact time. In conclusion, the ingredient combination in Duplalim is very effective in inactivating common viruses of domestic animals and poultry.
AB - Outbreaks of viral diseases in animals are a cause of concern for animal welfare and economics of animal production. One way to disrupt the cycle of infection is by combating viruses in the environment and prohibiting them from being transmitted to a new host. Viral contamination of the environment can be reduced using well-tested and efficacious disinfectants. Duplalim is a commercially available disinfectant consisting of 12% glutaraldehyde and 10% quaternary ammonium compounds. We evaluated this disinfectant for its efficacy against several viruses in poultry (n = 3), pigs (n = 5), dogs (n = 2), and cattle (n = 4). In suspension tests, 1:100 dilution of Duplalim was found to inactivate more than 99% of these 14 viruses in 15 min or less. The titers of a majority of these viruses decreased by ≥99.99% in <60 min of contact time. In conclusion, the ingredient combination in Duplalim is very effective in inactivating common viruses of domestic animals and poultry.
KW - disinfection
KW - Duplalim
KW - inactivation
KW - suspension test
KW - virus
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U2 - 10.3389/fvets.2023.1276031
DO - 10.3389/fvets.2023.1276031
M3 - Article
C2 - 38239742
AN - SCOPUS:85182457197
SN - 2297-1769
VL - 10
JO - Frontiers in Veterinary Science
JF - Frontiers in Veterinary Science
M1 - 1276031
ER -