Abstract
Aim. Excess body weight, obesity, and hypertension increase the risk of non-communicable diseases. The purpose of this study was to examine how body mass index (BMI) correlates with various indicators of circadian hemodynamics in young men and women. Subjects and Methods. ABPM at 30-min intervals for 2 to 7 days was carried out in 56 of 91 Kazakh university students, aged 21.1 ± 2.9 years. Data were analyzed chronobiologically to estimate the circadian rhythm characteristics of blood pressure (BP) and heart rate (HR). The latter were linearly regressed as a function of BMI, overall and for men and women separately. Results. There were 22.0 % students who were overweight or obese, and 15.4% were underweight. In clinically healthy Kazakh students, BMI correlated with the MESOR (rhythm-adjusted mean) of systolic (S) and diastolic (D) BP and HR, and with the daily average of the pulse-pressure product in young men. Such correlations were not found for young women. Conclusion. The weaker influence of BMI on BP and HR in women as compared to men may be accounted for by the action of estrogens, thought to offer cardio-protection.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 49-56 |
| Number of pages | 8 |
| Journal | World Heart Journal |
| Volume | 11 |
| Issue number | 1 |
| State | Published - 2019 |
Bibliographical note
Funding Information:This work was supported by a grant from the Ministry of Education and Science of the Republic of Kazakhstan, № AP05133311 “The study of the chronophysiological mechanisms of the human’s cardiovascular system’ adaptation to the environmental abiotic and socio-ecological factors”
Publisher Copyright:
© 2019 Nova Science Publishers, Inc.
