Investigation of paternal programming of breast cancer risk in female offspring in rodent models

Camile Castilho Fontelles; Raquel Santana da Cruz; Leena Hilakivi-Clarke; Sonia de Assis; Thomas Prates Ong

doi:10.1007/978-1-4939-7614-0_11

Investigation of paternal programming of breast cancer risk in female offspring in rodent models

Camile Castilho Fontelles, Raquel Santana da Cruz, Leena Hilakivi-Clarke, Sonia de Assis, Thomas Prates Ong

Research output: Chapter in Book/Report/Conference proceeding › Chapter

5 Scopus citations

Abstract

Emerging experimental evidence show that fathers’ experiences during preconception can influence their daughters’ risk of developing breast cancer. Here we describe detailed protocols for investigation in rats and mice of paternally mediated breast cancer risk programming effects.

Original language	English (US)
Title of host publication	Methods in Molecular Biology
Publisher	Humana Press Inc.
Pages	207-220
Number of pages	14
DOIs	https://doi.org/10.1007/978-1-4939-7614-0_11
State	Published - 2018
Externally published	Yes

Publication series

Name	Methods in Molecular Biology
Volume	1735
ISSN (Print)	1064-3745

Bibliographical note

Funding Information:
C.C.F. was a recipient of a Ph.D. scholarship from the Brazilian National Council for Scientific and Technological Development (CNPq; Proc. 153478/2012-8). T.P.O. is the recipient of a researcher fellowship from CNPq (Proc. 307910/2016-4) and is supported by grants from CNPq (Proc. 448501/2014-7), the Food Research Center (FoRC), and the São Paulo State Research Funding Agency (Proc. 2013/07914-8). S.D.A. is supported by grants from the National Institutes of Health (K22CA178309-01A1) and the American Cancer Society (Research Scholar Grant).

Publisher Copyright:
© 2018, Springer Science+Business Media, LLC.

Keywords

7,12-Dimethylbenz[a]anthracene
Breast cancer
Female offspring
Mammary gland development
Paternal programming
Preconceptional diet
Rodents

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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title = "Investigation of paternal programming of breast cancer risk in female offspring in rodent models",

abstract = "Emerging experimental evidence show that fathers{\textquoteright} experiences during preconception can influence their daughters{\textquoteright} risk of developing breast cancer. Here we describe detailed protocols for investigation in rats and mice of paternally mediated breast cancer risk programming effects.",

keywords = "7,12-Dimethylbenz[a]anthracene, Breast cancer, Female offspring, Mammary gland development, Paternal programming, Preconceptional diet, Rodents",

author = "Fontelles, {Camile Castilho} and {da Cruz}, {Raquel Santana} and Leena Hilakivi-Clarke and {de Assis}, Sonia and Ong, {Thomas Prates}",

note = "Funding Information: C.C.F. was a recipient of a Ph.D. scholarship from the Brazilian National Council for Scientific and Technological Development (CNPq; Proc. 153478/2012-8). T.P.O. is the recipient of a researcher fellowship from CNPq (Proc. 307910/2016-4) and is supported by grants from CNPq (Proc. 448501/2014-7), the Food Research Center (FoRC), and the S{\~a}o Paulo State Research Funding Agency (Proc. 2013/07914-8). S.D.A. is supported by grants from the National Institutes of Health (K22CA178309-01A1) and the American Cancer Society (Research Scholar Grant). Publisher Copyright: {\textcopyright} 2018, Springer Science+Business Media, LLC.",

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AU - da Cruz, Raquel Santana

AU - Hilakivi-Clarke, Leena

AU - de Assis, Sonia

AU - Ong, Thomas Prates

N1 - Funding Information: C.C.F. was a recipient of a Ph.D. scholarship from the Brazilian National Council for Scientific and Technological Development (CNPq; Proc. 153478/2012-8). T.P.O. is the recipient of a researcher fellowship from CNPq (Proc. 307910/2016-4) and is supported by grants from CNPq (Proc. 448501/2014-7), the Food Research Center (FoRC), and the São Paulo State Research Funding Agency (Proc. 2013/07914-8). S.D.A. is supported by grants from the National Institutes of Health (K22CA178309-01A1) and the American Cancer Society (Research Scholar Grant). Publisher Copyright: © 2018, Springer Science+Business Media, LLC.

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KW - Female offspring

KW - Mammary gland development

KW - Paternal programming

KW - Preconceptional diet

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Investigation of paternal programming of breast cancer risk in female offspring in rodent models

Abstract

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Bibliographical note

Keywords

UN SDGs

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