TY - JOUR
T1 - Lectins with potential for anti-cancer therapy
AU - Yau, Tammy
AU - Dan, Xiuli
AU - Ng, Charlene Cheuk Wing
AU - Ng, Tzi Bun
N1 - Publisher Copyright:
© 2015 by the authors; licensee MDPI.
PY - 2015/3/1
Y1 - 2015/3/1
N2 - This article reviews lectins of animal and plant origin that induce apoptosis and autophagy of cancer cells and hence possess the potential of being developed into anticancer drugs. Apoptosis-inducing lectins encompass galectins, C-type lectins, annexins, Haliotis discus discus lectin, Polygonatum odoratum lectin, mistletoe lectin, and concanavalin A, fucose-binding Dicentrarchus labrax lectin, and Strongylocentrotus purpuratus lectin, Polygonatum odoratum lectin, and mistletoe lectin, Polygonatum odoratum lectin, autophagy inducing lectins include annexins and Polygonatum odoratum lectin.
AB - This article reviews lectins of animal and plant origin that induce apoptosis and autophagy of cancer cells and hence possess the potential of being developed into anticancer drugs. Apoptosis-inducing lectins encompass galectins, C-type lectins, annexins, Haliotis discus discus lectin, Polygonatum odoratum lectin, mistletoe lectin, and concanavalin A, fucose-binding Dicentrarchus labrax lectin, and Strongylocentrotus purpuratus lectin, Polygonatum odoratum lectin, and mistletoe lectin, Polygonatum odoratum lectin, autophagy inducing lectins include annexins and Polygonatum odoratum lectin.
KW - Apoptosis
KW - Autophagy
KW - Cancer cells
KW - Lectins
UR - http://www.scopus.com/inward/record.url?scp=84929587322&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84929587322&partnerID=8YFLogxK
U2 - 10.3390/molecules20033791
DO - 10.3390/molecules20033791
M3 - Review article
C2 - 25730388
AN - SCOPUS:84929587322
SN - 1420-3049
VL - 20
SP - 3791
EP - 3810
JO - Molecules
JF - Molecules
IS - 3
ER -
