Abstract
Gross et al. present results of the EARLY PRO-TECT trial, a randomized controlled trial of ramipril versus placebo in children with early-stage Alport syndrome. Although under-enrolled and not a positive trial in the traditional sense, EARLY PRO-TECT does provide strong supportive evidence for both long-term safety and a clinical benefit of early treatment with angiotensin-converting enzyme inhibitors in slowing the progression of both albuminuria and estimated glomerular filtration rate decline in children with Alport syndrome.
Original language | English (US) |
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Pages (from-to) | 1104-1106 |
Number of pages | 3 |
Journal | Kidney international |
Volume | 97 |
Issue number | 6 |
DOIs |
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State | Published - Jun 2020 |
Bibliographical note
Publisher Copyright:© 2020 International Society of Nephrology
PubMed: MeSH publication types
- Journal Article
- Randomized Controlled Trial